Conventional and state-of-the-art detection methods of bovine spongiform encephalopathy (BSE)

M Olech - International Journal of Molecular Sciences, 2023 - mdpi.com
Bovine spongiform encephalopathy (BSE) is a fatal neurodegenerative disease that belongs
to a group of diseases known as transmissible spongiform encephalopathies (TSEs). It is …

The transmissible spongiform encephalopathies of livestock

JJ Greenlee, MHW Greenlee - ILAR journal, 2015 - academic.oup.com
Prion diseases or transmissible spongiform encephalopathies (TSEs) are fatal protein-
misfolding neurodegenerative diseases. TSEs have been described in several species …

Experimental transmission of the chronic wasting disease agent to swine after oral or intracranial inoculation

SJ Moore, MH West Greenlee, N Kondru… - Journal of …, 2017 - Am Soc Microbiol
Chronic wasting disease (CWD) is a naturally occurring, fatal neurodegenerative disease of
cervids. The potential for swine to serve as hosts for the agent of CWD is unknown. The …

Raccoons accumulate PrPSc after intracranial inoculation of the agents of chronic wasting disease or transmissible mink encephalopathy but not atypical scrapie

SJ Moore, JD Smith, JA Richt… - Journal of Veterinary …, 2019 - journals.sagepub.com
Prion diseases are neurodegenerative diseases characterized by the accumulation of
misfolded prion protein (PrPSc) in the brain and other tissues. Animal prion diseases include …

A new photoelectrochemical aptasensor for prion assay based on cyclodextrin and Rhodamine B

X Yan, J Li, R Yang, Y Li, X Zhang, J Chen - Sensors and Actuators B …, 2018 - Elsevier
Herein, a simple and novel photoelectrochemical (PEC) aptasensor for the detection of prion
protein was developed based on β-cyclodextrin (β-CD) and Rhodamine B (RhB). HS-β …

A sensitive electrochemical immunosensor for prion detection based on poly-β-cyclodextrin/gold nanoparticles/glassy carbon electrode

X Li, J Li, Y Liu, X Zhang, J Chen - Sensors and Actuators B: Chemical, 2017 - Elsevier
In this work, we developed a sensitive electrochemical immunosensor for prion detection
based on poly-β-cyclodextrin (Pβ-CD)/gold nanoparticles (AuNPs) modified electrode. Here …

Differential accumulation of misfolded prion strains in natural hosts of prion diseases

ZJ Lambert, JJ Greenlee, ED Cassmann… - Viruses, 2021 - mdpi.com
Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are a
group of neurodegenerative protein misfolding diseases that invariably cause death. TSEs …

A new electrochemical immunoassay for prion protein based on hybridization chain reaction with hemin/G-quadruplex DNAzyme

X Li, J Li, C Zhu, X Zhang, J Chen - Talanta, 2018 - Elsevier
In this work, a new electrochemical immunosensor was developed for prion protein assay
based on hybridization chain reaction (HCR) with hemin/G-quadruplex DNAzyme for signal …

[HTML][HTML] Increased attack rates and decreased incubation periods in raccoons with chronic wasting disease passaged through meadow voles

SJ Moore, CM Carlson, JR Schneider… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
Chronic wasting disease (CWD) is a naturally-occurring neurodegenerative disease of
cervids. Raccoons (Procyon lotor) and meadow voles (Microtus pennsylvanicus) have …

Detection of Pathognomonic Biomarker PrPSc and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases

H Eraña, JM Charco, E González-Miranda… - Biomolecules, 2020 - mdpi.com
Transmissible spongiform encephalopathies or prion diseases are rapidly progressive
neurodegenerative diseases, the clinical manifestation of which can resemble other …