Long noncoding RNA in cancer: wiring signaling circuitry
C Lin, L Yang - Trends in cell biology, 2018 - cell.com
Long noncoding RNAs (lncRNAs), which are encoded by a vast less explored region of the
human genome, may hold missing drivers of cancer and have gained attention recently as a …
human genome, may hold missing drivers of cancer and have gained attention recently as a …
[HTML][HTML] Human long noncoding RNA interactome: detection, characterization and function
M Kazimierczyk, MK Kasprowicz, ME Kasprzyk… - International journal of …, 2020 - mdpi.com
The application of a new generation of sequencing techniques has revealed that most of the
genome has already been transcribed. However, only a small part of the genome codes …
genome has already been transcribed. However, only a small part of the genome codes …
CRISPR/Cas9‐mediated mutagenesis of lncRNA1459 alters tomato fruit ripening
R Li, D Fu, B Zhu, Y Luo, H Zhu - The Plant Journal, 2018 - Wiley Online Library
With the development of high‐throughput sequencing, many long non‐coding RNA s (lnc
RNA s) have been found to play important roles in diverse biological processes. However …
RNA s) have been found to play important roles in diverse biological processes. However …
[HTML][HTML] Long non-coding RNAs in Oral squamous cell carcinoma: biologic function, mechanisms and clinical implications
L Zhang, X Meng, X Zhu, D Yang, R Chen, Y Jiang… - Molecular cancer, 2019 - Springer
There is growing evidence that regions of the genome that cannot encode proteins play an
important role in diseases. These regions are usually transcribed into long non-coding …
important role in diseases. These regions are usually transcribed into long non-coding …
Protein–DNA/RNA interactions: an overview of investigation methods in the-omics era
F Cozzolino, I Iacobucci, V Monaco… - Journal of Proteome …, 2021 - ACS Publications
The fields of application of functional proteomics are not limited to the study of protein–
protein interactions; they also extend to those involving protein complexes that bind DNA or …
protein interactions; they also extend to those involving protein complexes that bind DNA or …
LncADeep: an ab initio lncRNA identification and functional annotation tool based on deep learning
Motivation To characterize long non-coding RNAs (lncRNAs), both identifying and
functionally annotating them are essential to be addressed. Moreover, a comprehensive …
functionally annotating them are essential to be addressed. Moreover, a comprehensive …
From structure to function: Route to understanding lncRNA mechanism
J Graf, M Kretz - BioEssays, 2020 - Wiley Online Library
RNAs have emerged as a major target for diagnostics and therapeutics approaches.
Regulatory nonprotein‐coding RNAs (ncRNAs) in particular display remarkable versatility …
Regulatory nonprotein‐coding RNAs (ncRNAs) in particular display remarkable versatility …
Noncoding RNAs in neurodegeneration
E Salta, B De Strooper - Nature Reviews Neuroscience, 2017 - nature.com
The emerging complexity of the transcriptional landscape poses great challenges to our
conventional preconceptions of how the genome regulates brain function and dysfunction …
conventional preconceptions of how the genome regulates brain function and dysfunction …
Emerging roles of long non-coding RNAs in plant response to biotic and abiotic stresses
Spectacular progress in high-throughput transcriptome sequencing and expression profiling
using next-generation sequencing technologies have recently revolutionized molecular …
using next-generation sequencing technologies have recently revolutionized molecular …
[HTML][HTML] Long noncoding RNA functionality in imprinted domain regulation
WA MacDonald, MRW Mann - PLoS Genetics, 2020 - journals.plos.org
Genomic imprinting is a parent-of-origin dependent phenomenon that restricts transcription
to predominantly one parental allele. Since the discovery of the first long noncoding RNA …
to predominantly one parental allele. Since the discovery of the first long noncoding RNA …