The Earth is home to environments characterized by low pH, including the gastrointestinal
tract of vertebrates and large areas of acidic soil. Most bacteria are neutralophiles, but can …

The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …

Phenotypic variations between individual microbial cells play a key role in the resistance of
microbial pathogens to pharmacotherapies. Nevertheless, little is known about cell …

Antibiotic tolerance, or the ability of bacteria to survive antibiotic treatment in the absence of
genetic resistance, has been linked to chronic and recurrent infections. Tolerant cells are …

The interactions between bacteria and bacteriophage have important roles in the global
ecosystem; in turn changes in environmental parameters affect the interactions between …

Antibiotics effective against Gram‐negative ESKAPE pathogens are a critical area of unmet
need. Infections caused by these pathogens are not only difficult to treat but finding new …

One of the deepest branches in the tree of life separates the Archaea from the Bacteria.
These prokaryotic groups have distinct cellular systems including fundamentally different …

The acid stress response is an important factor influencing the transmission of intestinal
microbes such as the enterobacterium Escherichia coli. E. coli activates three inducible acid …

Antimicrobial resistance is an urgent threat to human health, and new antibacterial drugs are
desperately needed, as are research tools to aid in their discovery and development …

Biofilm formation is one of the crucial factors for virulence in Candida albicans, Escherichia
coli and their polymicrobial biofilm formed on medical prosthetics. In this study, high biofilm …