Bone substitutes are being increasingly used in surgery as over two millions bone grafting
procedures are performed worldwide per year. Autografts still represent the gold standard …

Control of inflammation is indispensable for optimal oral wound healing and tissue
regeneration. Several biomaterials have been used to enhance the regenerative outcomes; …

Steroid-associated osteonecrosis (SAON) often requires surgical core decompression (CD)
in the early stage for removal of necrotic bone to facilitate repair where bone grafts are …

Critical‐sized defects in bone, whether induced by primary tumor resection, trauma, or
selective surgery have in many cases presented insurmountable challenges to the current …

The management of periodontal tissue defects that result from periodontitis represents a
medical and socioeconomic challenge. Concerted efforts have been and still are being …

Over the last decade carboxymethyl chitosan (CMCS) has emerged as a promising
biopolymer for the development of new drug delivery systems and improved scaffolds along …

There is a growing socio-economic need for effective strategies to repair damaged bone
resulting from disease, trauma and surgical intervention. Bone tissue engineering has …

In osteochondral tissue engineering, cell recruitment, proliferation, differentiation, and
patterning are critical for forming biologically and structurally viable constructs for repair of …

The repair of infected bone defects is still challenging in the fields of orthopedics, oral
implantology and maxillofacial surgery. In these cases, the self-healing capacity of bone …

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