The coiled-coil domain-containing (CCDC) proteins have been implicated in a variety of
physiological and pathological processes. Their functional roles vary from their interaction …

The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate
targeting is facilitated by its co-factor Mtr4p/hMTR4, which links to RNA-binding protein …

Many long noncoding RNAs (lncRNAs) are unstable and rapidly degraded in the nucleus by
the nuclear exosome. An exosome adaptor complex called NEXT (nuclear exosome …

Cellular protein interaction networks are integral to host defence and immune signalling
pathways, which are often hijacked by viruses via protein interactions. However, the …

Rationale: Pulmonary arterial hypertension (PAH) is characterized by enhanced proliferation
of pulmonary artery smooth muscle cells (PASMCs) accompanying increased production of …

Aim This research aimed at clarifying the intracellular effect of SERPINE1 in the progression
of colon adenocarcinoma (COAD) and the underlying mechanism. Methods We obtained the …

Abstract Background Zinc finger C3H1 domain-containing protein (ZFC3H1) is differentially
expressed between primary tumor and the normal in most cancers. Additionally, a recent …

The present study was aimed to evaluate the expression profile of Zinc finger C3H1 domain-
containing protein (ZFC3H1) using bioinformatic analysis of public datasets from The …

Melanoma represents one of the most aggressive malignancies and has a high tendency to
metastasize. The present study aims to investigate the molecular mechanisms of two …

Background Prostate adenocarcinoma (PRAD) is a common tumor with a high mortality rate,
and advanced PRAD remains incurable. Exploring biomarkers related to PRAD prognosis …