Epidemiology and genomics of prostate cancer in Asian men
Prostate cancer is a global health problem, but incidence varies considerably across
different continents. Asia is traditionally considered a low-incidence area, but the incidence …
different continents. Asia is traditionally considered a low-incidence area, but the incidence …
The epidemiology of prostate cancer
CH Pernar, EM Ebot, KM Wilson… - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Prostate cancer is a major cause of disease and mortality among men, and each year 1.6
million men are diagnosed with and 366,000 men die of prostate cancer. In this review, we …
million men are diagnosed with and 366,000 men die of prostate cancer. In this review, we …
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants
The transferability and clinical value of genetic risk scores (GRSs) across populations
remain limited due to an imbalance in genetic studies across ancestrally diverse …
remain limited due to an imbalance in genetic studies across ancestrally diverse …
Epidemiology of prostate cancer in Asian countries
T Kimura, S Egawa - International journal of urology, 2018 - Wiley Online Library
The incidence of prostate cancer has been increasing worldwide in recent years. The
GLOBOCAN project showed that prostate cancer was the second most frequently diagnosed …
GLOBOCAN project showed that prostate cancer was the second most frequently diagnosed …
Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction
L Kachuri, RE Graff, K Smith-Byrne, TJ Meyers… - Nature …, 2020 - nature.com
Cancer risk is determined by a complex interplay of environmental and heritable factors.
Polygenic risk scores (PRS) provide a personalized genetic susceptibility profile that may be …
Polygenic risk scores (PRS) provide a personalized genetic susceptibility profile that may be …
Evidence of novel susceptibility variants for prostate cancer and a multiancestry polygenic risk score associated with aggressive disease in men of African ancestry
Background Genetic factors play an important role in prostate cancer (PCa) susceptibility.
Objective To discover common genetic variants contributing to the risk of PCa in men of …
Objective To discover common genetic variants contributing to the risk of PCa in men of …
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study
E Jorgenson, KK Thai, TJ Hoffmann, LC Sakoda… - Molecular …, 2017 - nature.com
Alcohol consumption is a complex trait determined by both genetic and environmental
factors, and is correlated with the risk of alcohol use disorders. Although a small number of …
factors, and is correlated with the risk of alcohol use disorders. Although a small number of …
Androgen receptor binding sites enabling genetic prediction of mortality due to prostate cancer in cancer-free subjects
Prostate cancer (PrCa) is the second most common cancer worldwide in males. While
strongly warranted, the prediction of mortality risk due to PrCa, especially before its …
strongly warranted, the prediction of mortality risk due to PrCa, especially before its …
African-American prostate cancer disparities
Abstract Purpose of Review The purpose of this review is to examine prostate cancer racial
disparities specific to the African-American population. Recent Findings African-American …
disparities specific to the African-American population. Recent Findings African-American …