The ontogeny of immunity during early life is of high importance as it shapes the immune
system for the entire course of life. The microbiome and the environment contribute to the …

The extreme vulnerability of preterm infants to invasive microbial infections has been
attributed to “immature” innate immune defenses. Monocytes are important innate immune …

Objective To evaluate the difference in 10-year neurocognitive outcomes between extremely
low gestational age newborns without bacteremia and those with suspected or confirmed …

Group B Streptococcus (GBS) is a common intestinal colonizer during the neonatal period,
but also may cause late-onset sepsis or meningitis in up to 0.5% of otherwise healthy …

Background Preterm infants show low blood levels of insulin-like growth factor 1 (IGF-1),
known to be negatively correlated with Interleukin-6 (IL-6). We hypothesized that circulating …

Preterm infants are uniquely susceptible to late‐onset sepsis that is frequently caused by the
skin commensal Staphylococcus epidermidis. Innate immune responses, particularly from …

Preterm infants are more susceptible to severe bacterial and viral infectious diseases than
their full-term counterparts. A major contributor to this increased susceptibility may be due to …

The aim of the present study was to examine constitutive signal transducer and activator of
transcription 3 (STAT3) phosphorylation in circulating leukocytes as a candidate biomarker …

Objective: Patent ductus arteriosus (PDA) is a commonly observed condition in preterm
infants. Prior studies have suggested a role for genetics in determining spontaneous ductal …

Background The incidence of type 1 diabetes mellitus (T1DM) has increased in recent
decades, as has the incidence of preterm births (< 37 weeks). We aimed to evaluate and …