Astrocytes are the most abundant cell type in the central nervous system (CNS), performing
complex functions in health and disease. It is now clear that multiple astrocyte subsets or …

The epidemic history of Zika virus began in 2007, with its emergence in Yap Island in the
western Pacific, followed in 2013–14 by a larger epidemic in French Polynesia, south …

Background Causes of mortality are a crucial input for health systems for identifying
appropriate interventions for child survival. We present an updated series of cause-specific …

Importance Zika virus infection can be prenatally passed from a pregnant woman to her
fetus. There is sufficient evidence to conclude that intrauterine Zika virus infection is a cause …

Background The signs and symptoms of Zika virus infection are usually mild and self-limited.
However, the disease has been linked to neurological complications such as Guillain-Barré …

Zika virus (ZIKV) has evolved into a global health threat because of its unexpected causal
link to microcephaly. Phylogenetic analysis reveals that contemporary epidemic strains have …

Throughout the last decade, chikungunya virus (CHIKV) and Zika virus (ZIKV) infections
have spread globally, causing a spectrum of disease that ranges from self-limited febrile …

Background The World Health Organization (WHO) stated in March 2016 that there was
scientific consensus that the mosquito-borne Zika virus was a cause of the neurological …

Background A Zika virus epidemic emerged in northeast Brazil in 2015 and was followed by
a striking increase in congenital microcephaly cases, triggering a declaration of an …

Congenital Zika virus infection can cause microcephaly and severe brain abnormalities. As
more information about the associated clinical syndrome becomes available, the phenotype …