Vascular endothelial growth factor A (VEGF-A), the founding member of the vascular
permeability factor (VPF)/VEGF family of proteins, is an important angiogenic cytokine with …

We performed a meta-analysis of all published studies relating intratumoural microvessel
density (MVD)(45 studies) or vascular endothelial growth factor (VEGF) expression (27 …

Angiogenesis is required for tumor growth and metastasis and, therefore, represents an
exciting target for cancer treatment. Angiogenesis is a complex process that is tightly …

Background Expression of intrinsic markers of tumour hypoxia and angiogenesis are
important predictors of radiotherapeutic, and possibly surgical, outcome in several cancers …

We aimed to assess the relationship of the angiogenic cytokines VEGF-A, VEGF-C, and
VEGF-D and their receptors VEGFR-2 and VEGFR-3 in the adenomacarcinoma sequence …

Abstract Background: Hypoxia-inducible factor 1 (HIF-1), a heterodimer comprising the
oxygen-regulated subunit, HIF-1α, and HIF-1β, mediates transcription of the gene for …

Abstract Background and Objective Anastomotic leakage is a serious complication after
arterial resection of rectal cancer. It has been found that anastomotic leakage is related to …

HIF‐1 is reported to transactivate expression of VEGF, which is an important angiogenic
factor. To determine whether HIF‐1α plays a role in angiogenesis through its regulation of …

Objective Published studies have evaluated the impact of stromal myofibroblasts on
prognosis in solid cancers. However, the results of these studies remain controversial. We …

AIMS: To identify the chemical constituents of volatile oil from blood orange (Citrus sinensis
(L) Osbeck) and understand the possible mechanisms of inhibition of colon cancer cell …