The future of computer-aided sperm analysis

ST Mortimer, G Van der Horst… - Asian journal of …, 2015 - journals.lww.com
Computer-aided sperm analysis (CASA) technology was developed in the late 1980s for
analyzing sperm movement characteristics or kinematics and has been highly successful in …

Machine learning for sperm selection

JB You, C McCallum, Y Wang, J Riordon… - Nature Reviews …, 2021 - nature.com
Infertility rates and the number of couples seeking fertility care have increased worldwide
over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are …

[HTML][HTML] Leukocytes and oxidative stress: dilemma for sperm function and male fertility

RR Henkel - Asian journal of andrology, 2011 - ncbi.nlm.nih.gov
Spermatozoa are constantly exposed to the interphase between oxidation through high
amounts of reactive oxygen species (ROS) and leukocytes, and reduction by means of …

Advances in sperm analysis: techniques, discoveries and applications

C Dai, Z Zhang, G Shan, LT Chu, Z Huang… - Nature Reviews …, 2021 - nature.com
Infertility affects one in six couples worldwide, and fertility continues to deteriorate globally,
partly owing to a decline in semen quality. Sperm analysis has a central role in diagnosing …

[HTML][HTML] Measurement and significance of sperm morphology

R Menkveld, CAG Holleboom… - Asian journal of …, 2011 - ncbi.nlm.nih.gov
The measurement or evaluation and clinical significance of human sperm morphology has
always been and still is a controversial aspect of the semen analysis for the determination of …

A novel deep learning method for automatic assessment of human sperm images

S Javadi, SA Mirroshandel - Computers in biology and medicine, 2019 - Elsevier
Sperm morphology analysis (SMA) is a very important factor in the diagnosis process of
male infertility. This research proposes a novel deep learning algorithm for malformation …

Compact and light-weight automated semen analysis platform using lensfree on-chip microscopy

TW Su, A Erlinger, D Tseng, A Ozcan - Analytical chemistry, 2010 - ACS Publications
We demonstrate a compact and lightweight platform to conduct automated semen analysis
using a lensfree on-chip microscope. This holographic on-chip imaging platform weighs∼ …

Reproductive outcomes predicted by phase imaging with computational specificity of spermatozoon ultrastructure

ME Kandel, M Rubessa, YR He… - Proceedings of the …, 2020 - National Acad Sciences
The ability to evaluate sperm at the microscopic level, at high-throughput, would be useful
for assisted reproductive technologies (ARTs), as it can allow specific selection of sperm …

The functional anatomy of the human spermatozoon: relating ultrastructure and function

D Mortimer - MHR: Basic science of reproductive medicine, 2018 - academic.oup.com
The Internet, magazine articles, and even biomedical journal articles, are full of cartoons of
spermatozoa that bear minimal resemblance to real spermatozoa, especially human …

Current perspectives of CASA applications in diverse mammalian spermatozoa

G van der Horst, L Maree… - … Fertility and Development, 2018 - CSIRO Publishing
Since the advent of computer-aided sperm analysis (CASA) some four decades ago,
advances in computer technology and software algorithms have helped establish it as a …