Stroke and acute myocardial infarction are leading causes of mortality worldwide. The latter
accounts for approximately 9 million deaths annually. In turn, ischemic stroke is a significant …

Acute ischemic stroke (AIS) afflicts millions of individuals worldwide. Despite the
advancements in thrombolysis and thrombectomy facilitating proximal large artery …

Stroke is a leading cause of mortality and long-term disability globally, with acute ischemic
stroke (AIS) being the most common subtype. Despite significant advances in reperfusion …

Hydrogen sulfide (H2S), a gas traditionally considered toxic, is now recognized as a vital
endogenous signaling molecule with a complex physiology. This comprehensive study …

Ischemic stroke (IS) is a disease of high death and disability worldwide with few medications
in clinical treatment. Neuroinflammation and oxidative stress are considered as crucial …

In the field of stroke thrombectomy, ineffective clinical and angiographic reperfusion after
successful recanalization has drawn attention. Partial or complete microcirculatory …

Ischemic stroke (IS) is a major cause of mortality and morbidity worldwide. Beyond
thrombolysis, strategies targeting anti-oxidative apoptosis and angiogenesis are considered …

Most acute ischemic stroke patients with large vessel occlusion require stent implantation for
complete recanalization. Yet, due to ischemia-reperfusion injury, over half of these patients …

A proportion of acute ischemic stroke (AIS) patients suffer from early neurological
deterioration (END) within 24 hours following intravenous thrombolysis (IVT), which greatly …

Circadian rhythm is a master process observed in nearly every type of cell throughout the
body, and it macroscopically regulates daily physiology. Recent clinical trials have revealed …