ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

PM Thompson, N Jahanshad, CRK Ching… - Translational …, 2020 - nature.com
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …

ENIGMA‐DTI: Translating reproducible white matter deficits into personalized vulnerability metrics in cross‐diagnostic psychiatric research

P Kochunov, LE Hong, EL Dennis… - Human brain …, 2022 - Wiley Online Library
The ENIGMA‐DTI (diffusion tensor imaging) workgroup supports analyses that examine the
effects of psychiatric, neurological, and developmental disorders on the white matter …

Diffuse axonal injury has a characteristic multidimensional MRI signature in the human brain

D Benjamini, D Iacono, ME Komlosh, DP Perl… - Brain, 2021 - academic.oup.com
Axonal injury is a major contributor to the clinical symptomatology in patients with traumatic
brain injury. Conventional neuroradiological tools, such as CT and MRI, are insensitive to …

Mapping astrogliosis in the individual human brain using multidimensional MRI

D Benjamini, DS Priemer, DP Perl, DL Brody… - Brain, 2023 - academic.oup.com
There are currently no non-invasive imaging methods available for astrogliosis assessment
or mapping in the central nervous system despite its essential role in the response to many …

Altered white matter microstructural organization in posttraumatic stress disorder across 3047 adults: results from the PGC-ENIGMA PTSD consortium

EL Dennis, SG Disner, N Fani, LE Salminen… - Molecular …, 2021 - nature.com
A growing number of studies have examined alterations in white matter organization in
people with posttraumatic stress disorder (PTSD) using diffusion MRI (dMRI), but the results …

Diffusion-weighted imaging in mild traumatic brain injury: a systematic review of the literature

HM Lindsey, CB Hodges, KM Greer, EA Wilde… - Neuropsychology …, 2023 - Springer
There is evidence that diffusion-weighted imaging (DWI) is able to detect tissue alterations
following mild traumatic brain injury (mTBI) that may not be observed on conventional …

ENIGMA brain injury: Framework, challenges, and opportunities

EL Dennis, D Baron, B Bartnik‐Olson… - Human brain …, 2022 - Wiley Online Library
Traumatic brain injury (TBI) is a major cause of disability worldwide, but the heterogeneous
nature of TBI with respect to injury severity and health comorbidities make patient outcome …

Behavioral and myelin-related abnormalities after blast-induced mild traumatic brain injury in mice

M Nonaka, WW Taylor, O Bukalo, LB Tucker… - Journal of …, 2021 - liebertpub.com
In civilian and military settings, mild traumatic brain injury (mTBI) is a common consequence
of impacts to the head, sudden blows to the body, and exposure to high-energy atmospheric …

White matter alterations in military service members with remote mild traumatic brain injury

S Kim, J Ollinger, C Song, S Raiciulescu… - JAMA network …, 2024 - jamanetwork.com
Importance Mild traumatic brain injury (mTBI) is the signature injury experienced by military
service members and is associated with poor neuropsychiatric outcomes. Yet, there is a lack …

Opposing white matter microstructure abnormalities in 22q11. 2 deletion and duplication carriers

J Seitz-Holland, M Lyons, L Kushan, A Lin… - Translational …, 2021 - nature.com
Deletions and duplications at the 22q11. 2 locus are associated with significant
neurodevelopmental and psychiatric morbidity. Previous diffusion-weighted magnetic …