Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

The physiological control of eating: signals, neurons, and networks

AG Watts, SE Kanoski, G Sanchez-Watts… - Physiological …, 2022 - journals.physiology.org
During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

The versatile tanycyte: a hypothalamic integrator of reproduction and energy metabolism

V Prevot, B Dehouck, A Sharif, P Ciofi… - Endocrine …, 2018 - academic.oup.com
The fertility and survival of an individual rely on the ability of the periphery to promptly,
effectively, and reproducibly communicate with brain neural networks that control …

From belly to brain: targeting the ghrelin receptor in appetite and food intake regulation

K Howick, BT Griffin, JF Cryan… - International journal of …, 2017 - mdpi.com
Ghrelin is the only known peripherally-derived orexigenic hormone, increasing appetite and
subsequent food intake. The ghrelinergic system has therefore received considerable …

N-terminal liver-expressed antimicrobial peptide 2 (LEAP2) region exhibits inverse agonist activity toward the ghrelin receptor

C M'Kadmi, A Cabral, F Barrile, J Giribaldi… - Journal of Medicinal …, 2018 - ACS Publications
The ghrelin receptor or growth hormone secretagogue receptor (GHSR) is a G-protein-
coupled receptor that controls growth hormone and insulin secretion, food intake, and …

Astroglia-specific contributions to the regulation of synapses, cognition and behaviour

M Augusto-Oliveira, GP Arrifano, PY Takeda… - Neuroscience & …, 2020 - Elsevier
Astrocytes are a heterogeneous population of neural cells with diverse structural, functional
and molecular characteristics responsible for homeostasis and protection of the central …

Characterization of the metabolic differences between male and female C57BL/6 mice

GO de Souza, F Wasinski, J Donato Jr - Life sciences, 2022 - Elsevier
Aims The present study aims to compare the responses between male and female C57BL/6
mice to multiple metabolic challenges to understand the importance of sex in the control of …

Ghrelin signalling on food reward: a salient link between the gut and the mesolimbic system

M Perello, SL Dickson - Journal of neuroendocrinology, 2015 - Wiley Online Library
'Hunger is the best spice'is an old and wise saying that acknowledges the fact that almost
any food tastes better when we are hungry. The neurobiological underpinnings of this lore …

[HTML][HTML] LEAP2 deletion in mice enhances ghrelin's actions as an orexigen and growth hormone secretagogue

K Shankar, NP Metzger, O Singh, BK Mani… - Molecular …, 2021 - Elsevier
Objective The hormone liver-expressed antimicrobial peptide-2 (LEAP2) is a recently
identified antagonist and an inverse agonist of the growth hormone secretagogue receptor …

Current understanding of the hypothalamic ghrelin pathways inducing appetite and adiposity

O Al Massadi, M López, M Tschöp, C Diéguez… - Trends in …, 2017 - cell.com
Ghrelin is a multifaceted regulator of metabolism. Ghrelin regulates energy balance in the
short term via induction of appetite and in the long term via increased body weight and …