Purpose. Guided tissue reconstruction can be performed to restore the supporting structure
of a previously lost tooth, which, in addition to maintaining beauty, preserves the function of …

Osteochondral (OC) repair is an extremely challenging topic due to the complex biphasic
structure and poor intrinsic regenerative capability of natural osteochondral tissue. In …

Despite the high regenerative capacity of bone tissue, there are some cases where bone
repair is insufficient for a complete functional and structural recovery after damage. Current …

The reconstruction of critical-sized segmental bone defects is a key challenge in orthopedics
because of its intractability despite technological advancements. To overcome this …

In the last decades, near‐infrared (NIR) light has attracted considerable attention due to its
unique properties and numerous potential applications in bioimaging and disease …

Craniofacial reconstruction requires robust bone of specified geometry for the repair to be
both functional and aesthetic. While native bone from elsewhere in the body can be …

Bone regeneration depends on a pool of bone/cartilage stem/progenitor cells and signaling
mechanisms regulating their differentiation. Using in vitro approach, we have shown that …

The rise of additive manufacturing has provided a paradigm shift in the fabrication of precise,
patient-specific implants that replicate the physical properties of native bone. However …

Cell fate determination of human mesenchymal stem/stromal cells (hMSCs) is precisely
regulated by lineage-specific transcription factors and epigenetic enzymes. We found that …

Recombinant human bone morphogenetic protein-2 (rhBMP-2) has shown potential in
maxillofacial surgery owing to its osteoinductive properties. However, concerns about its …