During adaptive immunity, B cells differentiate either into memory B cells or plasma cells and
produce antibodies against foreign antigens to fight infection. Additionally, they behave as …

Multiple myeloma (MM) is a haematological malignancy of plasma cells characterized by
substantial intraclonal genetic heterogeneity. Although therapeutic advances made in the …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

New approaches to stratify multiple myeloma patients based on prognosis and therapeutic
decision-making, or prediction, are needed since patients are currently managed in a similar …

The analysis of circulating tumor cells (CTCs) is an outstanding tool to provide insights into
the biology of metastatic cancers, to monitor disease progression and with potential for use …

Multiple myeloma, a plasma cell malignancy, is the second most common blood cancer.
Despite extensive research, disease heterogeneity is poorly characterized, hampering …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Genomic analyses of primary liver cancer samples reveal a complex mutational landscape
with vast intertumor and intratumor heterogeneity. Different primary liver tumors and …

The management of patients with metastatic renal cell carcinoma (RCC) has changed
dramatically over the past few years. Nephrectomy remains an important intervention for …

Liquid biopsies including circulating tumor cells (CTCs) and cell-free DNA (cfDNA) have
enabled minimally invasive characterization of many cancers, but are rarely analyzed …