[HTML][HTML] Electrospun fibers for the treatment of skin diseases

AL Gürtler, T Rades, A Heinz - Journal of Controlled Release, 2023 - Elsevier
Skin diseases are among the most common diseases in the global population and with the
growth of the aging population, they represent an increasing burden to healthcare systems …

Calreticulin: Endoplasmic reticulum Ca2+ gatekeeper

M Michalak - Journal of Cellular and Molecular Medicine, 2024 - Wiley Online Library
Endoplasmic reticulum (ER) luminal Ca2+ is vital for the function of the ER and regulates
many cellular processes. Calreticulin is a highly conserved, ER‐resident Ca2+ binding …

Electrospinning nanofibers as a dressing to treat diabetic wounds

EJ Jang, R Patel, M Patel - Pharmaceutics, 2023 - mdpi.com
Globally, diabetic mellitus (DM) is a common metabolic disease that effectively inhibits
insulin production, destroys pancreatic β cells, and consequently, promotes hyperglycemia …

Malate-Based Biodegradable Scaffolds Activate Cellular Energetic Metabolism for Accelerated Wound Healing

M Wu, Y Zhao, M Tao, M Fu, Y Wang… - … Applied Materials & …, 2023 - ACS Publications
The latest advancements in cellular bioenergetics have revealed the potential of transferring
chemical energy to biological energy for therapeutic applications. Despite efforts, a three …

Calreticulin: a multifunctional protein with potential therapeutic applications for chronic wounds

AP Sawaya, NM Vecin, JL Burgess, N Ojeh… - Frontiers in …, 2023 - frontiersin.org
Calreticulin is recognized as a multifunctional protein that serves an essential role in diverse
biological processes that include wound healing, modification and folding of proteins …

Epithelial-Mesenchymal Transition of Cancer Cells on Micropillar Arrays

R Liu, H Wang, J Ding - ACS Applied Bio Materials, 2024 - ACS Publications
Epithelial-mesenchymal transition (EMT) is critical for tumor invasion and many other cell-
relevant processes. While much progress has been made about EMT, no report concerns …

The Biologic IRL201805 Alters Immune Tolerance Leading to Prolonged Pharmacodynamics and Efficacy in Rheumatoid Arthritis Patients

C Hall, J Pleasance, O Hickman, B Kirkham… - International Journal of …, 2024 - mdpi.com
A homologue of binding immunoglobulin protein/BiP—IRL201805 alters the function of
immune cells in pre-clinical in vivo and in vitro studies. The aim of the study was to select …

Calreticulin accelerates corneal wound closure and mitigates fibrosis: Potential therapeutic applications

S Mishra, MA Manzanares, J Prater… - Journal of Cellular …, 2024 - Wiley Online Library
The processes involved in regeneration of cutaneous compared to corneal tissues involve
different intrinsic mechanisms. Importantly, cutaneous wounds involve healing by …

Gingival Fibroblasts Are Sensitive to Oral Cell Lysates Indicated by Their IL11 Expression

L Panahipour, AO Abbasabadi, R Gruber - Bioengineering, 2023 - mdpi.com
Damaged cells that appear as a consequence of invasive dental procedures or in response
to dental materials are supposed to release damage-associated signals. These damage …