Osteoarthritis (OA) is one of the most common causes of disability around the globe,
especially in aging populations. The main symptoms of OA are pain and loss of motion and …

Background Despite the popularity of microfracture as a first-line treatment for articular
cartilage defects in the knee, systematic information on its clinical efficacy for articular …

Osteoarthritis affects millions of people worldwide but current treatments using analgesics or
anti-inflammatory drugs only alleviate symptoms of this disease. Here, we present an …

Load-bearing tissues, such as muscle and cartilage, exhibit high elasticity, high toughness
and fast recovery, but have different stiffness (with cartilage being significantly stiffer than …

More than 32.5 million American adults suffer from osteoarthritis, and current treatments
including pain medicines and anti-inflammatory drugs only alleviate symptoms but do not …

Mitochondrial dysfunction and oxidative stress damage are hallmarks of osteoarthritis (OA).
Mesenchymal stem cell (MSC)-derived exosomes are important in intercellular mitochondria …

Articular cartilage defect repair is a problem that has long plagued clinicians. Although
mesenchymal stem cells (MSCs) have the potential to regenerate articular cartilage, they …

Background Osteoarthritis (OA) is the most common joint disease worldwide. In the past
decade, mesenchymal stem cells (MSCs) have been used widely for the treatment of OA. A …

Articular cartilage has limited self-regenerative capacity and the therapeutic methods for
cartilage defects are still dissatisfactory in clinic. Recent studies showed that exosomes …

Articular cartilage injuries experienced at an early age can lead to the development of
osteoarthritis later in life. In situ three‐dimensional (3D) printing is an exciting and innovative …