Human immunodeficiency virus type 1 (HIV-1) Tat is a multifunctional protein that contributes
to several pathological symptoms of HIV-1 infection as well as playing a critical role in virus …

Human immunodeficiency virus type 1 (HIV-1) encodes a transactivator of transcription (Tat)
protein, which has several functions that promote viral replication, pathogenesis, and …

We reported previously that Bcl-2 is paradoxically down-regulated in paclitaxel-resistant
cancer cells. We reveal here that paclitaxel directly targets Bcl-2 in the loop domain, thereby …

Tat is a viral protein secreted from HIV infected cells and extra cellular Tat is suspected to
prevent destruction of HIV infected cells from cells of the cellular immunity. The effect of anti …

The human immunodeficiency virus type 1 (HIV-1) trans-activator of transcription protein Tat
is an important factor in viral pathogenesis. In addition to its function as the key trans …

Macrophages are a reservoir for latent human immunodeficiency type 1 (HIV) infection and a
barrier to HIV eradication. In contrast to CD4+ T cells, macrophages are resistant to the …

Early events leading to the establishment of hepatitis C virus (HCV) infection are not
completely understood. We show that intact and dynamic microtubules play a key role in the …

Antiretroviral therapy has dramatically improved the lives of human immunodeficiency virus
1 (HIV-1) infected individuals. Nonetheless, HIV-associated neurocognitive disorders …

The 5′ leader of the human immunodeficiency virus type 1 (HIV-1) genomic RNA harbors
an internal ribosome entry site (IRES) that is functional during the G2/M phase of the cell …

Relatively little is known at the functional genomic level about the global host response to
human immunodeficiency virus type 1 (HIV-1) infection. Microarray analyses by several …