Lactate is a universal metabolite produced and released by all cells in the body.
Traditionally it was viewed as energy currency that is generated from pyruvate at the end of …

We report the first and enantioselective total syntheses of (+)-1-deacetylcaesalmin C,(+)-δ-
caesalpin,(+)-norcaesalpinin MC, and (+)-norcaesalpinin P. Salient features of the synthetic …

TMEM87s are eukaryotic transmembrane proteins with two members (TMEM87A and
TMEM87B) in humans. TMEM87s have proposed roles in protein transport to and from the …

Fibrosis, a pathological state characterized by the excessive accumulation of extracellular
matrix components, is primarily driven by the overactivation of fibroblasts. This condition …

Background Anatidae contains numerous waterfowl species with great economic value, but
the genetic diversity basis remains insufficiently investigated. Here, we report a chromosome …

Emerging evidence suggests that butyrate, a short-chain fatty acid, may have beneficial
effects on obesity and its associated metabolic comorbidities, but the related molecular …

Cardiac fibroblasts are crucial for scar formation and cardiac repair after myocardial
infarction (MI). Collagen triple helix repeat containing 1 (CTHRC1), an extracellular matrix …

The current investigation aims to study the embryonic dermis formed in the early stages of
development and identify the initial interstitial components of the dermis that serve as …

Single-nucleotide polymorphisms in G protein-coupled receptor 180 (GPR180) are
associated with hypertriglyceridemia. The aim of this study was to determine whether …

Objective Adipose tissue depots vary markedly in their ability to store and metabolize
triglycerides, undergo beige adipogenesis and susceptibility to metabolic disease. The …