Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

Apolipoprotein E (ApoE) is a multifunctional protein involved in lipid transport and
lipoprotein metabolism, mediating lipid distribution/redistribution in tissues and cells. It can …

Estrogens play a crucial physiological function in the brain; however, debates exist
concerning the role of estrogens in Alzheimer's disease (AD). Women during pre-, peri-, or …

We review progress towards greater mechanistic understanding and clinical translation of a
strategy to improve respiratory and non-respiratory motor function in people with …

Menopause is associated with cognitive deficits and brain atrophy, but the brain region and
cell-specific mechanisms are not fully understood. Here, we identify a sex hormone by age …

Psychedelics, also known as classical hallucinogens, affect processes related to perception,
cognition and sensory processing mostly via the serotonin 5-HT 2A receptor (5-HT 2A R) …

Menopause has been associated with subjective cognitive dysfunction and elevated rates of
depression. While menopausal hormone therapy (MHT) is Food and Drug Administration …

The communication between neurons constitutes the basis of all neural activities, and
synaptic vesicle exocytosis is the fundamental biological event that mediates most …

Human apolipoprotein E (ApoE) was first identified as a polymorphic gene in the 1970s;
however, the genetic association of ApoE genotypes with late-onset sporadic Alzheimer's …

Apolipoprotein E (ApoE) is the main cholesterol carrier of the brain and the ε4 gene variant
(APOE4) is the most prevalent genetic risk factor for Alzheimer's disease (AD), increasing …