Numerical simulation analysis of multi-scale computational fluid dynamics on hemodynamic parameters modulated by pulsatile working modes for the centrifugal and …

M Huo, GA Giridharan, P Sethu, P Qu, K Qin… - Computers in Biology …, 2024 - Elsevier
Continuous flow (CF) left ventricular assist devices (LVAD) operate at a constant speed
mode, which could result in increased risk of adverse events due to reduced vascular …

Effect of veno-arterial extracorporeal membrane oxygenation lower-extremity cannulation on intra-arterial flow characteristics, oxygen content, and thrombosis risk

Y Xi, Y Li, H Wang, A Sun, X Deng, Z Chen… - Computer Methods and …, 2024 - Elsevier
Purpose This study aimed to investigate the effects of lower-extremity cannulation on the
intra-arterial hemodynamic environment, oxygen content, blood damage, and thrombosis …

A Fluid-Structure Interaction Simulation on the Impact of Transcatheter Micro Ventricular Assist Devices on Aortic Valves

Y Wang, F He, P Hao, X Zhang - Computer Methods and Programs in …, 2024 - Elsevier
Abstract Background and Objective The implantation of ventricular assist devices (VADs)
has become an important treatment option for patients with heart failure. Aortic valve …

An in silico analysis of unsteady flow structures in a microaxial blood pump under a pulsating rotation speed

C Chen, M Zhang, P Hao, F He, X Zhang - Computer Methods and …, 2024 - Elsevier
Background and objective Ventricular assist devices (VADs) are generally designed to
perform continuous flow. However, it has been proven that continuous flow, which is not a …

Analysis of non-physiological shear stress-induced red blood cell trauma across different clinical support conditions of the blood pump

X Liu, Y Li, J Jia, H Wang, Y Xi, A Sun, L Wang… - Medical & Biological …, 2024 - Springer
Systematic research into device-induced red blood cell (RBC) damage beyond hemolysis,
including correlations between hemolysis and RBC-derived extracellular vesicles, remains …

A New Mathematical Model for Assessment of Bleeding and Thrombotic Risk in Three Different Types of Clinical Ventricular Assist Devices

Y Li, Z Chen - Asian-Pacific Conference on Medical and Biological …, 2023 - Springer
In this study, our new shear-induced thrombosis and bleeding mathematical model
(integrates variations in platelet and vWF morphology, function, and binding ability) was …

A Fluid-Structure Interaction Simulation on the Impact of Intervenient Ventricular Assist Devices on Aortic Valves

Y Wang, F He, P Hao, X Zhang - Available at SSRN 4725138 - papers.ssrn.com
The implantation of ventricular assist devices (VADs) has become an important treatment
option for patients with heart failure. Aortic valve insufficiency (AVI) is a common …