The role and mechanism of epithelial-to-mesenchymal transition in prostate cancer progression
In prostate cancer (PCa), similar to many other cancers, distant organ metastasis symbolizes
the beginning of the end disease, which eventually leads to cancer death. Many …
the beginning of the end disease, which eventually leads to cancer death. Many …
Pterostilbene: Mechanisms of its action as oncostatic agent in cell models and in vivo studies
Z Ma, X Zhang, L Xu, D Liu, S Di, W Li, J Zhang… - Pharmacological …, 2019 - Elsevier
Pterostilbene, a natural dimethylated analog of resveratrol, exerts pleiotropic anticancer
effects against a variety of cancer types. Due to the better lipophilic and oral absorption …
effects against a variety of cancer types. Due to the better lipophilic and oral absorption …
[HTML][HTML] Resveratrol regulates PTEN/Akt pathway through inhibition of MTA1/HDAC unit of the NuRD complex in prostate cancer
Abstract Metastasis associated protein 1 (MTA1) is a component of the nucleosome
remodeling and deacetylating (NuRD) complex which mediates gene silencing and is …
remodeling and deacetylating (NuRD) complex which mediates gene silencing and is …
Structure, expression and functions of MTA genes
R Kumar, RA Wang - Gene, 2016 - Elsevier
Metastatic associated proteins (MTA) are integrators of upstream regulatory signals with the
ability to act as master coregulators for modifying gene transcriptional activity. The MTA …
ability to act as master coregulators for modifying gene transcriptional activity. The MTA …
[HTML][HTML] Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer
Overexpression of the epigenetic modifier metastasis-associated protein 1 (MTA1) is
associated with aggressive human prostate cancer. The purpose of this study was to …
associated with aggressive human prostate cancer. The purpose of this study was to …
Targeting MTA1/HIF‐1α signaling by pterostilbene in combination with histone deacetylase inhibitor attenuates prostate cancer progression
The metastasis‐associated protein 1 (MTA 1)/histone deacetylase (HDAC) unit is a cancer
progression‐related epigenetic regulator, which is overexpressed in hormone‐refractory …
progression‐related epigenetic regulator, which is overexpressed in hormone‐refractory …
Interleukin-17 promotes migration and invasion of human cancer cells through upregulation of MTA1 expression
N Guo, G Shen, Y Zhang, AA Moustafa, D Ge… - Frontiers in …, 2019 - frontiersin.org
Interleukin-17 (IL-17) has been shown to promote development of prostate, colon, skin, lung,
breast, and pancreatic cancer. The purpose of this study was to determine if IL-17 regulates …
breast, and pancreatic cancer. The purpose of this study was to determine if IL-17 regulates …
Epigenetic potential of resveratrol and analogs in preclinical models of prostate cancer
Lifestyle, particularly diet, is a risk factor for prostate cancer. Dietary polyphenols such as
resveratrol possess anticancer properties and therefore have chemopreventive and …
resveratrol possess anticancer properties and therefore have chemopreventive and …
[HTML][HTML] Novel potential serological prostate cancer biomarkers using CT100+ cancer antigen microarray platform in a multi-cultural South African cohort
There is a growing need for high throughput diagnostic tools for early diagnosis and
treatment monitoring of prostate cancer (PCa) in Africa. The role of cancer-testis antigens …
treatment monitoring of prostate cancer (PCa) in Africa. The role of cancer-testis antigens …
Metastasis-associated protein 1-mediated antitumor and anticancer activity of dietary stilbenes for prostate cancer chemoprevention and therapy
AS Levenson - Seminars in cancer biology, 2022 - Elsevier
Dietary bioactive polyphenols that demonstrate beneficial biological functions including
antioxidant, anti-inflammatory, and anticancer activity hold immense promise as effective …
antioxidant, anti-inflammatory, and anticancer activity hold immense promise as effective …