[HTML][HTML] The spectrum of triple-negative breast disease: high-and low-grade lesions
Triple-negative breast cancer is viewed clinically as an aggressive subgroup of breast
cancer. In fact, most triple-negative breast cancers are poor-prognosis tumors with a …
cancer. In fact, most triple-negative breast cancers are poor-prognosis tumors with a …
Triple-negative breast cancer: the importance of molecular and histologic subtyping, and recognition of low-grade variants
Triple-negative breast cancers (TNBCs), defined by lack of expression of estrogen receptor,
progesterone receptor and HER2, account for 12–17% of breast cancers and are clinically …
progesterone receptor and HER2, account for 12–17% of breast cancers and are clinically …
Salivary gland organoid culture maintains distinct glandular properties of murine and human major salivary glands
YJ Yoon, D Kim, KY Tak, S Hwang, J Kim… - Nature …, 2022 - nature.com
Salivary glands that produce and secrete saliva, which is essential for lubrication, digestion,
immunity, and oral homeostasis, consist of diverse cells. The long-term maintenance of …
immunity, and oral homeostasis, consist of diverse cells. The long-term maintenance of …
Contemporary management of benign and malignant parotid tumors
J Thielker, M Grosheva, S Ihrler, A Wittig… - Frontiers in …, 2018 - frontiersin.org
To report the standard of care, interesting new findings and controversies about the
treatment of parotid tumors. Relevant and actual studies were searched in PubMed and …
treatment of parotid tumors. Relevant and actual studies were searched in PubMed and …
Salivary duct carcinoma: updates in histology, cytology, molecular biology, and treatment
M Nakaguro, Y Tada, WC Faquin… - Cancer …, 2020 - Wiley Online Library
Salivary duct carcinoma (SDC) is an aggressive subtype of primary salivary gland
carcinoma, often with an advanced stage at presentation and high rates of metastasis and …
carcinoma, often with an advanced stage at presentation and high rates of metastasis and …
Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas
FC Geyer, A Li, AD Papanastasiou, A Smith… - Nature …, 2018 - nature.com
Adenomyoepithelioma of the breast is a rare tumor characterized by epithelial−
myoepithelial differentiation, whose genetic underpinning is largely unknown. Here we show …
myoepithelial differentiation, whose genetic underpinning is largely unknown. Here we show …
PI3K-AKT-mTOR inhibitors in breast cancers: From tumor cell signaling to clinical trials
N Dey, P De, B Leyland-Jones - Pharmacology & therapeutics, 2017 - Elsevier
Breast cancer (BC) is the most common women cancer and second most common cause of
cancer death in women. A woman living in the United States has 12.3% lifetime risk of being …
cancer death in women. A woman living in the United States has 12.3% lifetime risk of being …
New advances in molecular breast cancer pathology
Breast cancer (BC) comprises a diverse spectrum of diseases featuring distinct presentation,
morphological, biological, and clinical phenotypes. BC behaviour and response to therapy …
morphological, biological, and clinical phenotypes. BC behaviour and response to therapy …
Diagnostic significance of HRAS mutations in epithelial-myoepithelial carcinomas exhibiting a broad histopathologic spectrum
M Urano, M Nakaguro, Y Yamamoto… - The American Journal …, 2019 - journals.lww.com
Epithelial-myoepithelial carcinoma (EMC) is a rare salivary gland tumor that is histologically
characterized by biphasic tubular structures composed of inner ductal and outer clear …
characterized by biphasic tubular structures composed of inner ductal and outer clear …
Profiling of 149 salivary duct carcinomas, carcinoma ex pleomorphic adenomas, and adenocarcinomas, not otherwise specified reveals actionable genomic …
K Wang, JS Russell, JD McDermott, JA Elvin… - Clinical cancer …, 2016 - AACR
Purpose: We sought to identify genomic alterations (GA) in salivary gland adenocarcinomas,
not otherwise specified (NOS), salivary duct carcinomas (SDC), carcinoma ex pleomorphic …
not otherwise specified (NOS), salivary duct carcinomas (SDC), carcinoma ex pleomorphic …