[HTML][HTML] Emerging roles of lysophospholipids in health and disease

ST Tan, T Ramesh, XR Toh, LN Nguyen - Progress in Lipid Research, 2020 - Elsevier
Lipids are abundant and play essential roles in human health and disease. The main
functions of lipids are building blocks for membrane biogenesis. However, lipids are also …

The blood–retina barrier in health and disease

F O'Leary, M Campbell - The FEBS journal, 2023 - Wiley Online Library
The blood–retina barrier (BRB) is the term used to define the properties of the retinal
capillaries and the retinal pigment epithelium (RPE), which separate the systemic circulation …

Lipid and lipoprotein metabolism in microglia

BA Loving, KD Bruce - Frontiers in physiology, 2020 - frontiersin.org
Microglia, once viewed as static bystanders with limited homeostatic functions, are now
considered key players in the development of neuroinflammatory and neurodegenerative …

Structural basis of omega-3 fatty acid transport across the blood–brain barrier

RJ Cater, GL Chua, SK Erramilli, JE Keener, BC Choy… - Nature, 2021 - nature.com
Docosahexaenoic acid is an omega-3 fatty acid that is essential for neurological
development and function, and it is supplied to the brain and eyes predominantly from …

[HTML][HTML] A new perspective on lipid research in age-related macular degeneration

EM van Leeuwen, E Emri, BMJ Merle, JM Colijn… - Progress in retinal and …, 2018 - Elsevier
There is an urgency to find new treatment strategies that could prevent or delay the onset or
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …

[HTML][HTML] Dynamic lipid turnover in photoreceptors and retinal pigment epithelium throughout life

D Lewandowski, CL Sander, A Tworak, F Gao… - Progress in retinal and …, 2022 - Elsevier
The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Choline: exploring the growing science on its benefits for moms and babies

HW Korsmo, X Jiang, MA Caudill - Nutrients, 2019 - mdpi.com
The importance of ensuring adequate choline intakes during pregnancy is increasingly
recognized. Choline is critical for a number of physiological processes during the prenatal …

[HTML][HTML] Brain docosahexaenoic acid uptake and metabolism

RJS Lacombe, R Chouinard-Watkins… - Molecular Aspects of …, 2018 - Elsevier
Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the
brain where it serves to regulate several important processes and, in addition, serves as a …

Structure and mechanism of blood–brain-barrier lipid transporter MFSD2A

CAP Wood, J Zhang, D Aydin, Y Xu, BJ Andreone… - Nature, 2021 - nature.com
MFSD2A is a sodium-dependent lysophosphatidylcholine symporter that is responsible for
the uptake of docosahexaenoic acid into the brain,, which is crucial for the development and …

Omega‐3 PUFA profoundly affect neural, physiological, and behavioural competences–Implications for systemic changes in trophic interactions

M Pilecky, L Závorka, MT Arts, MJ Kainz - Biological Reviews, 2021 - Wiley Online Library
In recent decades, much conceptual thinking in trophic ecology has been guided by theories
of nutrient limitation and the flow of elements, such as carbon and nitrogen, within and …