Leishmaniasis (visceral and cutaneous), Chagas disease and human African
trypanosomiasis cause substantial death and morbidity, particularly in low-and middle …

Parasitic diseases, such as sleeping sickness, Chagas disease and malaria, remain a major
cause of morbidity and mortality worldwide, but particularly in tropical, developing countries …

Approximately 20% of sleeping sickness patients exhibit respiratory complications, however,
with a largely unknown role of the parasite. Here we show that tsetse fly-transmitted …

Trypanosoma brucei is a protozoan parasite that causes human and animal African
trypanosomiases (HAT and AAT). In the mammalian host, the parasite lives entirely …

African trypanosomes are responsible for important diseases of humans and animals in sub-
Saharan Africa. The best-studied species is Trypanosoma brucei, which is characterized by …

Background The diagnosis of gambiense human African trypanosomiasis (gHAT) typically
involves 2 steps: a serological screen, followed by the detection of living trypanosome …

Neglected tropical diseases (NTDs) constitute a group of approximately 20 infectious
diseases that mainly affect the impoverished population without basic sanitation in tropical …

Background To achieve elimination of Human African Trypanosomiasis (HAT) caused by
Trypanosoma brucei gambiense (gHAT), the development of highly sensitive diagnostics is …

Background Neglected tropical diseases are responsible for considerable morbidity and
mortality in low-income populations. International efforts have reduced their global burden …

Trypanosoma brucei parasites are the causative agents of African trypanosomiasis in
humans, as well as surra, nagana, and dourine in animals. According to current widely used …