Psychiatric face of COVID-19
L Steardo Jr, L Steardo, A Verkhratsky - Translational psychiatry, 2020 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) represents a severe multiorgan
pathology which, besides cardio-respiratory manifestations, affects the function of the central …
pathology which, besides cardio-respiratory manifestations, affects the function of the central …
Climate change, environment pollution, COVID-19 pandemic and mental health
D Marazziti, P Cianconi, F Mucci, L Foresi… - Science of the total …, 2021 - Elsevier
Converging data would indicate the existence of possible relationships between climate
change, environmental pollution and epidemics/pandemics, such as the current one due to …
change, environmental pollution and epidemics/pandemics, such as the current one due to …
Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex
E Gerrits, LAA Giannini, N Brouwer, S Melhem… - Nature …, 2022 - nature.com
Frontotemporal dementia (FTD) is the second most prevalent form of early-onset dementia,
affecting predominantly frontal and temporal cerebral lobes. Heterozygous mutations in the …
affecting predominantly frontal and temporal cerebral lobes. Heterozygous mutations in the …
[HTML][HTML] ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids
Frontotemporal dementia (FTD) because of MAPT mutation causes pathological
accumulation of tau and glutamatergic cortical neuronal death by unknown mechanisms. We …
accumulation of tau and glutamatergic cortical neuronal death by unknown mechanisms. We …
Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
Frontotemporal dementia, where do we stand? A narrative review
A Antonioni, EM Raho, P Lopriore, AP Pace… - International journal of …, 2023 - mdpi.com
Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …
Neuroinflammation: a potential risk for dementia
Dementia is a neurodegenerative condition that is considered a major factor contributing to
cognitive decline that reduces independent function. Pathophysiological pathways are not …
cognitive decline that reduces independent function. Pathophysiological pathways are not …
A predictive coding framework of allostatic–interoceptive overload in frontotemporal dementia
Recent allostatic–interoceptive explanations using predictive coding models propose that
efficient regulation of the body's internal milieu is necessary to correctly anticipate …
efficient regulation of the body's internal milieu is necessary to correctly anticipate …
Creutzfeldt-Jakob disease in a man with COVID-19: SARS-CoV-2-accelerated neurodegeneration?
We describe a man whose first manifestations of Creutzfeldt-Jakob disease occurred in
tandem with symptomatic onset of coronavirus disease 2019 (COVID-19). Drawing from …
tandem with symptomatic onset of coronavirus disease 2019 (COVID-19). Drawing from …
Extracellular tau stimulates phagocytosis of living neurons by activated microglia via Toll-like 4 receptor–NLRP3 inflammasome–caspase-1 signalling axis
K Pampuscenko, R Morkuniene, L Krasauskas… - Scientific reports, 2023 - nature.com
In tauopathies, abnormal deposition of intracellular tau protein followed by gradual elevation
of tau in cerebrospinal fluids and neuronal loss has been documented, however, the …
of tau in cerebrospinal fluids and neuronal loss has been documented, however, the …