Novel noninvasive approaches to the treatment of obesity: from pharmacotherapy to gene therapy

AM Angelidi, MJ Belanger, A Kokkinos… - Endocrine …, 2022 - academic.oup.com
Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …

Targeting programmed cell death to improve stem cell therapy: implications for treating diabetes and diabetes-related diseases

Q Zhang, XX Wan, XM Hu, WJ Zhao, XX Ban… - Frontiers in Cell and …, 2021 - frontiersin.org
Stem cell therapies have shown promising therapeutic effects in restoring damaged tissue
and promoting functional repair in a wide range of human diseases. Generations of insulin …

Favorable effect of sodium–glucose cotransporter 2 inhibitor, dapagliflozin, on non‐alcoholic fatty liver disease compared with pioglitazone

KY Cho, A Nakamura, K Omori… - Journal of Diabetes …, 2021 - Wiley Online Library
Abstract Aims/Introduction Sodium–glucose cotransporter 2 inhibitors, as well as
thiazolidines, suppress nonalcoholic fatty liver disease (NAFLD); however, few comparative …

Effects of the dual sodium–glucose linked transporter inhibitor, licogliflozin vs placebo or empagliflozin in patients with type 2 diabetes and heart failure

RA de Boer, J Núñez, P Kozlovski… - British journal of …, 2020 - Wiley Online Library
Aims Explore the efficacy, safety and tolerability of the dual sodium–glucose cotransporter
(SGLT) 1 and 2 inhibitor, licogliflozin in patients with type‐2 diabetes mellitus (T2DM) and …

Circulating cardiac biomarkers in diabetes mellitus: a new dawn for risk stratification—a narrative review

AE Berezin, AA Berezin - Diabetes Therapy, 2020 - Springer
The aim of this narrative review is to update the current knowledge on the differential choice
of circulating cardiac biomarkers in patients with prediabetes and established type 2 …

Risk of diabetic ketoacidosis of SGLT2 inhibitors in patients with type 2 diabetes: a systematic review and network meta-analysis of randomized controlled trials

S Yang, Y Liu, S Zhang, F Wu, D Liu, Q Wu… - Frontiers in …, 2023 - frontiersin.org
Background: Sodium–glucose cotransporter-2 (SGLT2) inhibitors have proven to be
effective in improving glycemic control in patients with type 2 diabetes mellitus (T2DM) …

Sodium-glucose cotransporter 2 (SGLT-2) inhibitors and microvascular outcomes in patients with type 2 diabetes: systematic review and meta-analysis

EG Dorsey-Treviño, JG González-González… - Journal of …, 2020 - Springer
Purpose The effect of the sodium-glucose 2 (SGLT-2) inhibitors on microvascular
complications remains uncertain. We performed a systematic review to determine the …

How should rheumatologists manage glucocorticoid-induced hyperglycemia?

H Nakamura, Y Fujieda, A Nakamura… - Modern …, 2021 - academic.oup.com
Glucocorticoid-induced hyperglycemia (GIH) is an important complication to be managed by
rheumatologists as it can affect morbidity and mortality of patients. Before administration of …

Lowering of blood pressure and pulse rate by switching from DPP-4 inhibitor to luseogliflozin in patients with type 2 diabetes complicated with hypertension: A …

R Hashimoto-Kameda, KY Cho, H Nomoto… - Diabetes research and …, 2021 - Elsevier
Aims Sodium-glucose cotransporter-2 inhibitor (SGLT2i) reduces clinic blood pressure (BP),
but the effects on BP circadian rhythm remain unclear. The present study aimed to determine …

Influence of Dapagliflozin Dosing on Low‐Density Lipoprotein Cholesterol in Type 2 Diabetes Mellitus: A Systematic Literature Review and Meta‐Analysis

S Martha, PH Jangam… - The Journal of Clinical …, 2024 - Wiley Online Library
A systematic literature review and meta‐analysis was performed to evaluate the effects of
dapagliflozin on low‐density lipoprotein (LDL) cholesterol in type 2 diabetes mellitus. Data …