[HTML][HTML] Efficacy of antiviral therapies for COVID-19: a systematic review of randomized controlled trials

CTR Vegivinti, KW Evanson, H Lyons, I Akosman… - BMC Infectious …, 2022 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) continues to pose a significant
threat to public health worldwide. The purpose of this study was to review current evidence …

[HTML][HTML] Efficacy of COVID-19 treatments: a Bayesian network meta-analysis of randomized controlled trials

C Zhang, H Jin, YF Wen, G Yin - Frontiers in Public Health, 2021 - frontiersin.org
Background: We provided a comprehensive evaluation of efficacy of available treatments for
coronavirus disease 2019 (COVID-19). Methods: We searched for candidate COVID-19 …

[HTML][HTML] The efficacy and adverse effects of favipiravir on patients with COVID-19: A systematic review and meta-analysis of published clinical trials and observational …

DT Hung, S Ghula, JMA Aziz, AM Makram… - International Journal of …, 2022 - Elsevier
Objectives This study aimed to evaluate the efficacy and adverse events of favipiravir in
patients with COVID-19. Methods Our protocol was registered on PROSPERO …

[HTML][HTML] After the hurricane: Anti-COVID-19 drugs development, molecular mechanisms of action and future perspectives

HO Khalifa, YM Al Ramahi - International Journal of Molecular Sciences, 2024 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a new coronavirus in
the Coronaviridae family. The COVID-19 pandemic, caused by SARS-CoV-2, has …

[HTML][HTML] Favipiravir effectiveness and safety in hospitalized moderate-severe COVID-19 patients: observational prospective multicenter investigation in Saudi Arabia

S Al-Muhsen, NS Al-Numair… - Frontiers in …, 2022 - frontiersin.org
Objectives There are limited data on the efficacy and safety of favipiravir antiviral in
coronavirus disease 2019 (COVID-19), particularly in the more progressed disease phase …

[HTML][HTML] Current status of therapeutic alternatives for COVID-19: A narrative review

AT Aslan, M Akova - Le infezioni in medicina, 2021 - ncbi.nlm.nih.gov
Since December 2019, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
infection has exploded and led to a global crisis. Currently, the global case numbers topped …

[HTML][HTML] Effectiveness of favipiravir on nonsevere, early-stage COVID-19 in Japan: a large observational study using the COVID-19 Registry Japan

S Tsuzuki, K Hayakawa, Y Doi, T Shinozaki… - Infectious diseases and …, 2022 - Springer
Introduction Several randomized controlled trials have compared the effectiveness of
favipiravir with that of placebo. However, evidence regarding its effect on nonsevere, early …

Progress, pitfalls, and path forward of drug repurposing for COVID-19 treatment

NS Taibe, MA Kord, MA Badawy… - Therapeutic …, 2022 - journals.sagepub.com
On 30 January 2020, the World Health Organization (WHO) declared the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic a public health emergency of …

Favipiravir-based treatment for outcomes of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials

SH Lan, CC Lai, SP Chang, LC Lu… - Expert Review of …, 2022 - Taylor & Francis
Background This meta-analysis of randomized controlled trials (RCTs) investigated the
clinical efficacy and safety of favipiravir for patients with mild-to-critical COVID-19. Methods …

[HTML][HTML] Guidance for the pharmacological management of COVID-19 in the emergency setting

MH Temsah, M Al-Jelaify, ZA Memish - Expert opinion on …, 2022 - Taylor & Francis
Since the early days of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
pandemic, therapeutic trials into pharmacological management of coronavirus-2019 (COVID …