A general framework for modelling trade‐offs in adaptive behaviour

AI Houston, L Fromhage, JM McNamara - Biological Reviews, 2024 - Wiley Online Library
An animal's behaviour can influence many variables, such as its energy reserves, its risk of
injury or mortality, and its rate of reproduction. To identify the optimal action in a given …

Is aging an inevitable characteristic of organic life or an evolutionary adaptation?

PV Lidsky, J Yuan, JM Rulison… - Biochemistry (Moscow …, 2022 - Springer
Aging is an evolutionary paradox. Several hypotheses have been proposed to explain it, but
none fully explains all the biochemical and ecologic data accumulated over decades of …

[HTML][HTML] Aging clocks based on accumulating stochastic variation

DH Meyer, B Schumacher - Nature Aging, 2024 - nature.com
Aging clocks have provided one of the most important recent breakthroughs in the biology of
aging, and may provide indicators for the effectiveness of interventions in the aging process …

Accurate aging clocks based on accumulating stochastic variation

B Schumacher, D Meyer - 2023 - researchsquare.com
Aging clocks have provided one of the most significant recent breakthroughs in the biology
of aging. Such clocks allow the determination of chronological and increasingly also …

Putting zoo animal cancer into perspective

M Clauss, DWH Müller - Zoo Biology, 2024 - Wiley Online Library
As part of a comparative research agenda that promises insights that help extend the human
lifespan and combat cancer, cancer prevalence in zoo animals has received recent …

Exploring patterns of human mortality and aging: a reliability theory viewpoint

LA Gavrilov, NS Gavrilova - Biochemistry (Moscow), 2024 - Springer
The most important manifestation of aging is an increased risk of death with advancing age,
a mortality pattern characterized by empirical regularities known as mortality laws. We …

[PDF][PDF] Solitary living species age too, and fast!

F Criscuolo, VA Viblanc, C Schradin - Trends in Ecology & Evolution, 2023 - hal.science
Lidsky and Andino claim the pathogen control hypothesis (PCH) has more explanatory
power than current theories on the evolution of ageing [1]. The PCH, based on kin selection …

[PDF][PDF] Quick Guide to Evolutionary Medicine in Neuroimmunomodulation: Why" Evolved for the Benefit of the Species" Is Not a Valid Argument.

C Schradin, AV Jaeggi, F Criscuolo - Neuroimmunomodulation, 2024 - karger.com
Background: Evolutionary medicine builds on evolutionary biology and explains why natural
selection has left us vulnerable to disease. Unfortunately, several misunderstandings exist in …

[HTML][HTML] Somatic mutation as an explanation for epigenetic aging

Z Koch, A Li, DS Evans, S Cummings, T Ideker - bioRxiv, 2023 - ncbi.nlm.nih.gov
DNA methylation marks have recently been used to build models known as “epigenetic
clocks” which predict calendar age. As methylation of cytosine promotes C-to-T mutations …

[PDF][PDF] Reconsidering life history theory amid infectious diseases

PV Lidsky, J Yuan, R Andino - Trends in Ecology & Evolution, 2023 - researchgate.net
The pathogen control evolutionary hypothesis (PCH) of aging was critically analyzed by
Criscuolo et al.[1]. According to PCH, a shorter lifespan might have evolved to eliminate …