In less than a decade, analyses of ancient genomes have transformed our understanding of
the Indigenous peopling and population history of the Americas. These studies have shown …

Abstract Cytochrome P450 2D6 (CYP2D6) plays an important role in the metabolism and
bioactivation of about 25% of clinically used drugs including many antidepressants …

Prevotella copri is a common human gut microbe that has been both positively and
negatively associated with host health. In a cross-continent meta-analysis exploiting> 6,500 …

INTRODUCTION The consensus view on the peopling of the Americas is that ancestors of
modern Native Americans entered the Americas from Siberia via the Bering Land Bridge …

The exact timing, route, and process of the initial peopling of the Americas remains uncertain
despite much research. Archaeological evidence indicates the presence of humans as far as …

For societies with writing systems, hereditary leadership is documented as one of the
hallmarks of early political complexity and governance. In contrast, it is unknown whether …

Kennewick Man, referred to as the Ancient One by Native Americans, is a male human
skeleton discovered in Washington state (USA) in 1996 and initially radiocarbon dated to …

It has been argued recently that the initial dispersal of anatomically modern humans from
Africa to southern Asia occurred before the volcanic “supereruption” of the Mount Toba …

A general introduction to the origins and history of Latin American populations is followed by
a systematic review of the data from molecular autosomal assessments of the …

Human populations, along with those of many other species, are thought to have contracted
into a number of refuge areas at the height of the last Ice Age. European populations are …