Role of Lactobacillus reuteri in Human Health and Diseases

Q Mu, VJ Tavella, XM Luo - Frontiers in microbiology, 2018 - frontiersin.org
Lactobacillus reuteri (L. reuteri) is a well-studied probiotic bacterium that can colonize a
large number of mammals. In humans, L. reuteri is found in different body sites, including the …

Intestinal epithelial glycosylation in homeostasis and gut microbiota interactions in IBD

MR Kudelka, SR Stowell, RD Cummings… - Nature reviews …, 2020 - nature.com
Inflammatory bowel disease (IBD) affects 6.8 million people globally. A variety of factors
have been implicated in IBD pathogenesis, including host genetics, immune dysregulation …

Experimental models to study intestinal microbes–mucus interactions in health and disease

L Etienne-Mesmin, B Chassaing… - FEMS microbiology …, 2019 - academic.oup.com
ABSTRACT A close symbiotic relationship exists between the intestinal microbiota and its
host. A critical component of gut homeostasis is the presence of a mucus layer covering the …

Lactobacillus Cell Surface Proteins Involved in Interaction with Mucus and Extracellular Matrix Components

L Muscariello, B De Siena, R Marasco - Current Microbiology, 2020 - Springer
The gut microbiota is a complex microbial ecosystem where bacteria, through mutual
interactions, cooperate in maintaining of wellbeing and health. Lactobacilli are among the …

Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus

CD Owen, LE Tailford, S Monaco, T Šuligoj… - Nature …, 2017 - nature.com
Ruminococcus gnavus is a human gut symbiont wherein the ability to degrade mucins is
mediated by an intramolecular trans-sialidase (Rg NanH). Rg NanH comprises a GH33 …

The effects of diet and gut microbiota on the regulation of intestinal mucin glycosylation

D Qu, G Wang, L Yu, F Tian, W Chen, Q Zhai - Carbohydrate polymers, 2021 - Elsevier
Intestinal mucins glycosylation is regulated by host cues and environmental signals from the
microbiome and diets. However, the mechanisms responsible for the dialogue between …

Investigation of changes in saliva in radiotherapy-induced head neck cancer patients

C Winter, R Keimel, M Gugatschka, D Kolb… - International journal of …, 2021 - mdpi.com
The intact function of the salivary glands is of utmost importance for oral health. During
radiotherapy in patients with head and neck tumors, the salivary glands can be damaged …

Probing the expression and adhesion of glycans involved in Helicobacter pylori infection

D Sijmons, S Collett, C Soliman, AJ Guy, AM Scott… - Scientific Reports, 2024 - nature.com
Helicobacter pylori infects approximately half the human population and has an unusual
infective niche of the human stomach. Helicobacter pylori is a major cause of gastritis and …

Quantifying and engineering mucus adhesion of probiotics

ZJS Mays, TC Chappell, NU Nair - ACS synthetic biology, 2020 - ACS Publications
Mucus in the gastrointestinal (GI) tract is the primary point-of-interaction between humans
and their gut microbiota. This intimates that mucus not only ensures protection against …

Bacterial adhesins, the pathogenic weapons to trick host defense arsenal

S Patel, N Mathivanan, A Goyal - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Adhesins are bacterial proteins with host cell adhesive properties. These proteins occur in
diverse architectures, ranging from capsules, vesicles, pili, fimbri, to enzymes. These …