G-quadruplexes and their ligands: Biophysical methods to unravel G-quadruplex/ligand interactions
Progress in the design of G-quadruplex (G4) binding ligands relies on the availability of
approaches that assess the binding mode and nature of the interactions between G4 …
approaches that assess the binding mode and nature of the interactions between G4 …
Recent Update on Targeting c-MYC G-Quadruplexes by Small Molecules for Anticancer Therapeutics
R Chaudhuri, S Bhattacharya, J Dash… - Journal of Medicinal …, 2020 - ACS Publications
Guanine-rich DNA sequences have the propensity to adopt four-stranded tetrahelical G-
quadruplex (G4) structures that are overrepresented in gene promoters. The structural …
quadruplex (G4) structures that are overrepresented in gene promoters. The structural …
A difunctional electrochemiluminescence sensor based on Ru-MOFs and strand-displacement-amplification reaction for ultrasensitive detection of Hg2+ and Ag+
A label free difunctional electrochemiluminescence (ECL) sensor for the ultrasensitive
detection of mercury ions (Hg 2+) and silver ions (Ag+) was constructed based on Ru (bpy) 3 …
detection of mercury ions (Hg 2+) and silver ions (Ag+) was constructed based on Ru (bpy) 3 …
[HTML][HTML] Performance of unique magnetic nanoparticles in biomedicine
M Binandeh - European Journal of Medicinal Chemistry Reports, 2022 - Elsevier
Much research has been done in the past on the use of nanoparticles in all biological and
medical fields. One of the most important issues in this case is the use of nanoparticles …
medical fields. One of the most important issues in this case is the use of nanoparticles …
In situ formation of transcriptional modulators using non-canonical DNA i-motifs
Non-canonical DNA i-motifs and G-quadruplexes are postulated as genetic switches for the
transcriptional regulation of proto-oncogenes. However, in comparison to G-quadruplexes …
transcriptional regulation of proto-oncogenes. However, in comparison to G-quadruplexes …
Label-free detection of LncRNA in cancer cells with human telomere G-quadruplex DNA-thioflavin T binding-induced fluorescence
S Jiang, Q Liu, WJ Liu, L Cui, CY Zhang - Sensors and Actuators B …, 2022 - Elsevier
The long noncoding RNAs (lncRNAs) are engaged in multiple biological processes and are
often abnormally expressed in various cancers. Although great progress has been made in …
often abnormally expressed in various cancers. Although great progress has been made in …
Gold nanoparticle-based photo-cross-linking strategy for cellular target identification of supercomplex molecular systems
L Yao, M Liao, JK Wang, J Wang, D Liu, PF Tu… - Analytical …, 2022 - ACS Publications
Cellular target identification plays an essential role in innovative drug development and
pharmacological mechanism elucidation. However, very few practical experimental …
pharmacological mechanism elucidation. However, very few practical experimental …
The association between diet quality indices and oxidative stress biomarkers in male footballers and healthy active controls
Objective The aim of the present study was the association between the relationship
between Dietary Quality Index-International (DQI-I) and Healthy Eating Index (HEI) and the …
between Dietary Quality Index-International (DQI-I) and Healthy Eating Index (HEI) and the …
Checkerboard arranged G4 nanostructure-supported electrochemical platform and its application to unique bio-enzymes examination
X Ren, Q Zhang, L Qin, K Hu, Z Guo, S Wang, Y Hu - Bioelectrochemistry, 2023 - Elsevier
In this study, a checkerboard arranged G4 nanostructure-supported electrochemical platform
is developed well for the application to unique bio-enzymes examination. Herein, we focus …
is developed well for the application to unique bio-enzymes examination. Herein, we focus …
Beyond the primary structure of nucleic acids: potential roles of epigenetics and noncanonical structures in the regulations of plant growth and stress responses
A Volná, M Bartas, J Nezval, R Pech, P Pečinka… - Plant Abiotic Stress …, 2023 - Springer
Epigenetics deals with changes in gene expression that are not caused by modifications in
the primary sequence of nucleic acids. These changes beyond primary structures of nucleic …
the primary sequence of nucleic acids. These changes beyond primary structures of nucleic …