Targeting vascular (endothelial) dysfunction

A Daiber, S Steven, A Weber… - British journal of …, 2017 - Wiley Online Library
Cardiovascular diseases are major contributors to global deaths and disability‐adjusted life
years, with hypertension a significant risk factor for all causes of death. The endothelium that …

[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach… - Redox biology, 2017 - Elsevier
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

[HTML][HTML] Redox-related biomarkers in human cardiovascular disease-classical footprints and beyond

A Daiber, O Hahad, I Andreadou, S Steven, S Daub… - Redox Biology, 2021 - Elsevier
Global epidemiological studies show that chronic non-communicable diseases such as
atherosclerosis and metabolic disorders represent the leading cause of premature mortality …

Engineering intelligent nanosystems for enhanced medical imaging

GT van Moolenbroek, T Patiño, J Llop… - Advanced Intelligent …, 2020 - Wiley Online Library
Medical imaging serves to obtain anatomical and physiological data, supporting medical
diagnostics as well as providing therapeutic evaluation and guidance. A variety of contrast …

Toward in vivo detection of hydrogen peroxide with ultrasound molecular imaging

ES Olson, J Orozco, Z Wu, CD Malone, B Yi, W Gao… - Biomaterials, 2013 - Elsevier
We present a new class of ultrasound molecular imaging agents that extend upon the
design of micromotors that are designed to move through fluids by catalyzing hydrogen …

Endothelial dysfunction: an intermediate clinical feature between urolithiasis and cardiovascular diseases

J Saenz-Medina, M Muñoz, C Rodriguez… - International Journal of …, 2022 - mdpi.com
An epidemiological relationship between urolithiasis and cardiovascular diseases has
extensively been reported. Endothelial dysfunction is an early pathogenic event in …

Redox biomarkers in cardiovascular medicine

K Karimi Galougahi, C Antoniades… - European heart …, 2015 - academic.oup.com
The central role of oxidative signalling in cardiovascular pathophysiology positions biometric
measures of redox state as excellent markers for research and clinical application. However …

[HTML][HTML] Taking up the cudgels for the traditional reactive oxygen and nitrogen species detection assays and their use in the cardiovascular system

A Daiber, M Oelze, S Steven, S Kröller-Schön… - Redox biology, 2017 - Elsevier
Reactive oxygen and nitrogen species (RONS such as H 2 O 2, nitric oxide) confer redox
regulation of essential cellular functions (eg differentiation, proliferation, migration …

Visualizing novel concepts of cardiovascular calcification

J Hjortnaes, SEP New, E Aikawa - Trends in cardiovascular medicine, 2013 - Elsevier
Cardiovascular calcification is currently viewed as an active disease process similar to
embryonic bone formation. Cardiovascular calcification mainly affects the aortic valve and …

Imaging reactive oxygen species-induced modifications in living systems

G Maulucci, G Bačić, L Bridal… - Antioxidants & redox …, 2016 - liebertpub.com
Abstract Significance: Reactive Oxygen Species (ROS) may regulate signaling, ion
channels, transcription factors, and biosynthetic processes. ROS-related diseases can be …