Intervertebral disc degeneration—Current therapeutic options and challenges
Degeneration of the intervertebral disc (IVD) is a normal part of aging. Due to the spine's
declining function and the development of pain, it may affect one's physical health, mental …
declining function and the development of pain, it may affect one's physical health, mental …
Genetic alterations in intervertebral disc disease
Background Intervertebral disc degeneration (IVDD) is considered a multifactorial disease
that is influenced by both environmental and genetic factors. The last two decades of …
that is influenced by both environmental and genetic factors. The last two decades of …
Toward regulatory effects of curcumin on transforming growth factor-beta across different diseases: a review
M Ashrafizadeh, A Zarrabi, K Hushmandi… - Frontiers in …, 2020 - frontiersin.org
Immune response, proliferation, migration and angiogenesis are juts a few of cellular events
that are regulated by transforming growth factor-β (TGF-β) in cells. A number of studies have …
that are regulated by transforming growth factor-β (TGF-β) in cells. A number of studies have …
Association of collagen I, IX and vitamin D receptor gene polymorphisms with radiological severity of intervertebral disc degeneration in Southern European Ancestor
Purpose Several genomic loci have been previously found to be associated with
intervertebral disc degeneration, so far. Data are mostly derived from northern European …
intervertebral disc degeneration, so far. Data are mostly derived from northern European …
Targeting autophagy for developing new therapeutic strategy in intervertebral disc degeneration
Intervertebral disc degeneration (IVDD) is a prevalent cause of low back pain. IVDD is
characterized by abnormal expression of extracellular matrix components such as collagen …
characterized by abnormal expression of extracellular matrix components such as collagen …
Genetic background of degenerative disc disease in the lumbar spine
Y Kawaguchi - Spine surgery and related research, 2018 - jstage.jst.go.jp
This is a review paper on the topic of genetic background of degenerative disc diseases in
the lumbar spine. Lumbar disc diseases (LDDs), such as lumbar disc degeneration and …
the lumbar spine. Lumbar disc diseases (LDDs), such as lumbar disc degeneration and …
Influence of single nucleotide polymorphisms on rifampin pharmacokinetics in tuberculosis patients
Rifampin (RF) is metabolized in the liver into an active metabolite 25-desacetylrifampin and
excreted almost equally via biliary and renal routes. Various influx and efflux transporters …
excreted almost equally via biliary and renal routes. Various influx and efflux transporters …
Biomarkers for intervertebral disc and associated back pain: From diagnosis to disease prognosis and personalized treatment
Biomarkers are commonly recognized as objective indicators of a medical state or clinical
outcome and have been widely used as clinical and diagnostic tools and surrogate …
outcome and have been widely used as clinical and diagnostic tools and surrogate …
[HTML][HTML] Biomarkers for intervertebral disc and associated back pain: From diagnosis to disease prognosis and personalized treatment
CL Pereira, S Grad, RM Gonçalves - JOR spine, 2023 - ncbi.nlm.nih.gov
Biomarkers are commonly recognized as objective indicators of a medical state or clinical
outcome and have been widely used as clinical and diagnostic tools and surrogate …
outcome and have been widely used as clinical and diagnostic tools and surrogate …
Vitamin D Receptor gene polymorphisms and plasma levels are associated with lumbar disc degeneration
Q Yang, Y Liu, Y Guan, X Zhan, Z Xiao, H Jiang… - Scientific Reports, 2019 - nature.com
The purpose of this study was to investigate the association of Vitamin D Receptor (VDR)
gene polymorphisms and VDR levels with lumbar disc degeneration (LDD). TaqMan SNP …
gene polymorphisms and VDR levels with lumbar disc degeneration (LDD). TaqMan SNP …