The roles of histone variants in fine-tuning chromatin organization and function

S Martire, LA Banaszynski - Nature reviews Molecular cell biology, 2020 - nature.com
Histones serve to both package and organize DNA within the nucleus. In addition to histone
post-translational modification and chromatin remodelling complexes, histone variants …

Histone variants at a glance

PB Talbert, S Henikoff - Journal of Cell Science, 2021 - journals.biologists.com
Eukaryotic nucleosomes organize chromatin by wrapping 147 bp of DNA around a histone
core particle comprising two molecules each of histone H2A, H2B, H3 and H4. The DNA …

The genetic and epigenetic landscape of the Arabidopsis centromeres

M Naish, M Alonge, P Wlodzimierz, AJ Tock… - Science, 2021 - science.org
INTRODUCTION The centromeres of eukaryotic chromosomes assemble the multiprotein
kinetochore complex and thereby position attachment to the spindle microtubules, allowing …

Histone variants on the move: substrates for chromatin dynamics

PB Talbert, S Henikoff - Nature reviews Molecular cell biology, 2017 - nature.com
Most histones are assembled into nucleosomes behind the replication fork to package newly
synthesized DNA. By contrast, histone variants, which are encoded by separate genes, are …

Epigenetic regulation of thermomorphogenesis and heat stress tolerance

G Perrella, I Bäurle, M van Zanten - New Phytologist, 2022 - Wiley Online Library
Many environmental conditions fluctuate and organisms need to respond effectively. This is
especially true for temperature cues that can change in minutes to seasons and often follow …

Integrated genome browser: visual analytics platform for genomics

NH Freese, DC Norris, AE Loraine - Bioinformatics, 2016 - academic.oup.com
Motivation: Genome browsers that support fast navigation through vast datasets and provide
interactive visual analytics functions can help scientists achieve deeper insight into …

DDM1-mediated R-loop resolution and H2A. Z exclusion facilitates heterochromatin formation in Arabidopsis

J Zhou, X Lei, S Shafiq, W Zhang, Q Li, K Li, J Zhu… - Science …, 2023 - science.org
Programmed constitutive heterochromatin silencing is essential for eukaryotic genome
regulation, yet the initial step of this process is ambiguous. A large proportion of R-loops …

[HTML][HTML] The INO80 chromatin remodeling complex promotes thermomorphogenesis by connecting H2A. Z eviction and active transcription in Arabidopsis

M Xue, H Zhang, F Zhao, T Zhao, H Li, D Jiang - Molecular Plant, 2021 - cell.com
Global warming poses a major threat to plant growth and crop production. In some plants,
including Arabidopsis thaliana, elevated temperatures induce a series of morphological and …

[HTML][HTML] Molecular complexes at euchromatin, heterochromatin and centromeric chromatin

O Morrison, J Thakur - International Journal of Molecular Sciences, 2021 - mdpi.com
Chromatin consists of a complex of DNA and histone proteins as its core components and
plays an important role in both packaging DNA and regulating DNA metabolic pathways …

[HTML][HTML] Transposition favors the generation of large effect mutations that may facilitate rapid adaption

L Quadrana, M Etcheverry, A Gilly, E Caillieux… - Nature …, 2019 - nature.com
Transposable elements (TEs) are mobile parasitic sequences that have been repeatedly
coopted during evolution to generate new functions and rewire gene regulatory networks …