Long-term survival with glioblastoma multiforme

D Krex, B Klink, C Hartmann, A Von Deimling, T Pietsch… - Brain, 2007 - academic.oup.com
The median survival of glioblastoma patients is∼ 12 months. However, 3–5% of the patients
survives for more than 3 years and are referred to as long-term survivors. The clinical and …

CNS complications of radiotherapy and chemotherapy

C Soussain, D Ricard, JR Fike, JJ Mazeron… - The lancet, 2009 - thelancet.com
Treatment-induced CNS toxicity remains a major cause of morbidity in patients with cancer.
Advances in the design of safe radiation procedures have been counterbalanced by …

Cancer therapy-associated CNS neuropathology: an update and review of the literature

A Perry, RE Schmidt - Acta neuropathologica, 2006 - Springer
Standard therapeutic options for brain tumors include surgery, radiation, and chemotherapy.
Unfortunately, these same therapies pose risks of neurotoxicity, the most common long-term …

Brain metastases

AD Norden, PY Wen, S Kesari - Current opinion in neurology, 2005 - journals.lww.com
Patients with brain metastases are now eligible for a number of treatment options that are
increasingly likely to improve outcomes. Randomized, prospective trials are necessary to …

Laser interstitial thermal therapy in the management of brain metastasis and radiation necrosis after radiosurgery: an overview

M Sharma, S Balasubramanian, D Silva… - Expert review of …, 2016 - Taylor & Francis
With advances in stereotactic and neuroimaging techniques, various minimally invasive
image-guided techniques have gained widespread acceptance in the field of neuro …

Gamma Knife radiosurgery to the surgical cavity following resection of brain metastases

J Jagannathan, CP Yen, DK Ray, D Schlesinger… - Journal of …, 2009 - thejns.org
Object This study evaluated the efficacy of postoperative Gamma Knife surgery (GKS) to the
tumor cavity following gross-total resection of a brain metastasis. Methods A retrospective …

Delayed brain radiation necrosis: pathological review and new molecular targets for treatment

M Furuse, N Nonoguchi, S Kawabata… - Medical Molecular …, 2015 - Springer
Delayed radiation necrosis is a well-known adverse event following radiotherapy for brain
diseases and has been studied since the 1930s. The primary pathogenesis is thought to be …

Surgical treatment of brain metastasis: a review

M Mut - Clinical neurology and neurosurgery, 2012 - Elsevier
Brain metastasis is the most common intracranial tumor in adults. Currently, treatment of
brain metastasis requires multidisciplinary approach tailored for each individual patient …

Relationship between volume, dose and local control in stereotactic radiosurgery of brain metastasis

R Molenaar, R Wiggenraad… - British journal of …, 2009 - Taylor & Francis
The aim of this study is to analyse the efficacy of linear accelerator stereotactic radiosurgery
(SRS) on prognostic factors, local control rate and survival in patients with brain metastasis …

Cerebral radiation necrosis

A Na, N Haghigi, KJ Drummond - Asia‐Pacific Journal of …, 2014 - Wiley Online Library
Cerebral radiation‐induced injury ranges from acute reversible edema to late irreversible
radiation necrosis (RN). Cerebral RN is poorly responsive to treatment, is associated with …