Axonal transport is essential for neuronal function, and many neurodevelopmental and
neurodegenerative diseases result from mutations in the axonal transport machinery …

Eukaryotic cells use cytoskeletal motor proteins to transport many different intracellular
cargos. Numerous kinesins and myosins have evolved to cope with the various transport …

The endocytic pathway is essential for processes that define how cells interact with their
environment, including receptor signalling, cell adhesion and migration, pathogen entry …

The microtubule motors kinesin and dynein function collectively to drive vesicular transport.
High-resolution tracking of vesicle motility in the cell indicates that transport is often …

Post‐translational modifications (PTM s) of α/β‐tubulin are believed to regulate interactions
with microtubule‐binding proteins. A well‐characterized PTM involves in the removal and re …

We report that microtubule (MT) nucleation at the Golgi apparatus requires AKAP450, a
centrosomal γ‐TuRC‐interacting protein that also forms a distinct network associated with …

Dynactin is a required cofactor for the minus-end-directed microtubule motor cytoplasmic
dynein. Mutations within the highly conserved CAP-Gly domain of dynactin cause …

Long-range retrograde axonal transport in neurons is driven exclusively by the microtubule
motor cytoplasmic dynein. The efficient initiation of dynein-mediated transport from the distal …

The distinctive morphology of neurons, with complex dendritic arbors and extensive axons,
presents spatial challenges for intracellular signal transduction. The endosomal system …

The chaperonin-containing tailless complex polypeptide 1 (CCT) is required in vivo for the
folding of newly synthesized tubulin and actin proteins and is thus intrinsically connected to …