Cardiovascular disease, which can lead to angina and shortness of breath, remains one of
the most serious threats to human health. Owing to its imperceptible symptoms, it is difficult …

Melatonin is a pleiotropic, indole secreted, and synthesized by the human pineal gland.
Melatonin has biological effects including anti-apoptosis, protecting mitochondria, anti …

Despite significant advances in the treatment of myocardial ischemia-reperfusion (I/R) injury,
coronary circulation is a so far neglected target of cardioprotection. In this study, we …

Myocardial infarction is characterized by sudden ischemia and cardiomyocyte death.
Mitochondria have critical roles in regulating cardiomyocyte viability and can sustain …

Mfn2 is a mitochondrial fusion protein with bioenergetic functions implicated in the
pathophysiology of neuronal and metabolic disorders. Understanding the bioenergetic …

Long-term ingestion of arsenicals, a heterogeneous group of toxic compounds, has been
associated with a wide spectrum of human pathologies, which include various malignancies …

Arsenite is an important carcinogen and toxic compound, causing various deleterious effects
through multiple mechanisms. In this review, we focused on mitochondrial ROS (mitoROS) …

Oxygen is a critical factor for most organisms and this is especially true for aquatic animals.
Unfortunately, high-density aquaculture farming practices and environmental degradation …

Mitochondria may be transferred from cell to cell in the central nervous system and this
process may help defend neurons against injury and disease. But how mitochondria …

Arsenite, a well-established human carcinogen and toxic compound, promotes the formation
of mitochondrial superoxide (mitoO 2− radical dot) via a Ca 2+-dependent mechanism, in …