Mammals have two specialized vascular circulatory systems: the blood vasculature and the
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …

Sox transcription factors play widespread roles during development; however, their versatile
funtions have a relatively simple basis: the binding of a Sox protein alone to DNA does not …

In mammals, specification of the three major germ layers occurs during gastrulation, when
cells ingressing through the primitive streak differentiate into the precursor cells of major …

Hair is a primary characteristic of mammals, and exerts a wide range of functions including
thermoregulation, physical protection, sensory activity, and social interactions. The hair shaft …

The growth of lymphatic vessels (lymphangiogenesis) is actively involved in a number of
pathological processes including tissue inflammation and tumor dissemination but is …

The lymphatic vasculature forms a vessel network that drains interstitial fluid from tissues
and returns it to the blood. Lymphatic vessels are also an essential part of the body's …

Lymphatic anomalies include a variety of developmental and/or functional defects affecting
the lymphatic vessels: sporadic and familial forms of primary lymphedema, secondary …

Clinical conditions causing hair loss, such as androgenetic alopecia, alopecia areata, and
scarring alopecia, can be psychologically devastating to individuals and are the target of a …

Members of the SOX family of transcription factors are found throughout the animal kingdom,
are characterized by the presence of a DNA-binding HMG domain, and are involved in a …

The circulatory system is the first organ system to develop in the vertebrate embryo and is
critical throughout gestation for the delivery of oxygen and nutrients to, as well as removal of …