Background Inflammatory diseases of the nail, including nail psoriasis and nail lichen
planus, are associated with significant disease burden and have a negative impact on …

Recent studies on molecular pathways have elucidated novel therapeutic approaches in
inflammatory and autoimmune skin disorders. Specifically, the dysregulation of the Janus …

Introduction Numerous cutaneous dermatoses mediated by cytokines depend on the JAK
STAT pathway for intracellular signaling. JAK inhibitors form a useful therapeutic approach …

Lichen planus (LP), an idiopathic, multifaceted chronic inflammatory disease with a
heterogeneous clinical presentation, affects approximately 0.5–1% of the population. The …

JAK inhibitors target specific inflammatory cytokines involved in various inflammatory
diseases. Four molecules have been approved for dermatological use: upadacitinib …

Lichen planus is a chronic inflammatory disorder that may cause significant nail changes
and impair daily life. Nail lichen planus presents a therapeutic challenge, as the condition is …

Erosive oral lichen planus (EOLP) represents a significant challenge in dental and medical
management due to its chronic inflammatory nature, painful symptoms, and impact on …

Lichen planus (LP) is a chronic inflammatory skin disease that affects cutaneous and
mucosal sites and is often recalcitrant to topical therapies. Erosive lichen planus (ELP) is a …

Nail lichen planus (NLP) is a chronic inflammatory disease of unknown etiology and has
been recognized as a nail potentially critical disorder, which can be severe and rapidly …

Lichen planus pigmentosum (LPP) is a rare, pigmented variant of lichen planus that is
characterized by hyperpigmented, dark brown to gray-black macules in sun-exposed areas …