Human genetics and malaria resistance

SN Kariuki, TN Williams - Human genetics, 2020 - Springer
Malaria has been the pre-eminent cause of early mortality in many parts of the world
throughout much of the last five thousand years and, as a result, it is the strongest force for …

Malaria parasites: the great escape

L Rénia, YS Goh - Frontiers in immunology, 2016 - frontiersin.org
Parasites of the genus Plasmodium have a complex life cycle. They alternate between their
final mosquito host and their intermediate hosts. The parasite can be either extra-or …

Plasmodium vivax infections of Duffy-negative erythrocytes: historically undetected or a recent adaptation?

K Gunalan, A Niangaly, MA Thera, OK Doumbo… - Trends in …, 2018 - cell.com
Plasmodium vivax is the main cause of malarial disease in Asia and South America.
Plasmodium vivax infection was thought to be absent in African populations who are Duffy …

African Plasmodium vivax malaria improbably rare or benign

JK Baird - Trends in Parasitology, 2022 - cell.com
The overwhelming dominance of Duffy blood group negativity among most people living in
sub-Saharan Africa has been considered the basis of their protection from endemic …

Prevalence and risk of Plasmodium vivax infection among Duffy-negative individuals: a systematic review and meta-analysis

P Wilairatana, FR Masangkay, KU Kotepui… - Scientific Reports, 2022 - nature.com
A better understanding of the occurrence and risk of Plasmodium vivax infection among
Duffy-negative individuals is required to guide further research on these infections across …

Role of Plasmodium vivax Duffy-binding protein 1 in invasion of Duffy-null Africans

K Gunalan, E Lo, JB Hostetler… - Proceedings of the …, 2016 - National Acad Sciences
The ability of the malaria parasite Plasmodium vivax to invade erythrocytes is dependent on
the expression of the Duffy blood group antigen on erythrocytes. Consequently, Africans …

Genomic analysis of Plasmodium vivax describes patterns of connectivity and putative drivers of adaptation in Ethiopia

AM Kebede, E Sutanto, H Trimarsanto… - Scientific Reports, 2023 - nature.com
Ethiopia has the greatest burden of Plasmodium vivax in Africa, but little is known about the
epidemiological landscape of parasites across the country. We analysed the genomic …

[HTML][HTML] Plasmodium vivax infections over 3 years in Duffy blood group negative Malians in Bandiagara, Mali

A Niangaly, K Gunalan, A Ouattara… - The American journal …, 2017 - ncbi.nlm.nih.gov
Plasmodium vivax was thought to infect only the erythrocytes of Duffy blood group positive
people. In the last decade, P. vivax has appeared throughout Africa, both in areas where …

Molecular evidence of Plasmodium vivax infection in Duffy negative symptomatic individuals from Dschang, West Cameroon

G Russo, G Faggioni, GM Paganotti… - Malaria journal, 2017 - Springer
Background Plasmodium vivax infection is known to be rare in West/Central Africa, the most
accepted explanation being the lack of expression of erythroid Duffy antigen in the local …

Transmission dynamics of co-endemic Plasmodium vivax and P. falciparum in Ethiopia and prevalence of antimalarial resistant genotypes

E Lo, E Hemming-Schroeder, D Yewhalaw… - PLoS neglected …, 2017 - journals.plos.org
Ethiopia is one of the few African countries where Plasmodium vivax is co-endemic with P.
falciparum. Malaria transmission is seasonal and transmission intensity varies mainly by …