Neurobiology of chronic mild stress: parallels to major depression

MN Hill, KGC Hellemans, P Verma, BB Gorzalka… - Neuroscience & …, 2012 - Elsevier
The chronic mild (or unpredictable/variable) stress (CMS) model was developed as an
animal model of depression more than 20 years ago. The foundation of this model was that …

Stress and memory: behavioral effects and neurobiological mechanisms

C Sandi, MT Pinelo-Nava - Neural plasticity, 2007 - Wiley Online Library
Stress is a potent modulator of learning and memory processes. Although there have been a
few attempts in the literature to explain the diversity of effects (including facilitating …

Astaxanthin ameliorates doxorubicin-induced cognitive impairment (chemobrain) in experimental rat model: impact on oxidative, inflammatory, and apoptotic …

SE El-Agamy, AK Abdel-Aziz, S Wahdan, A Esmat… - Molecular …, 2018 - Springer
Chemobrain refers to a common sequelae experienced by 15–80% of cancer patients
exposed to chemotherapeutics. The antineoplastic agent doxorubicin (DOX) has been …

Biomarkers for Alzheimer's disease in saliva: a systematic review

HS Gleerup, SG Hasselbalch, AH Simonsen - Disease markers, 2019 - Wiley Online Library
Background. The histopathological changes of Alzheimer's disease (AD) are detectable
decades prior to its clinical expression. However, there is a need for an early, inexpensive …

Alterations in monoamine levels and oxidative systems in frontal cortex, striatum, and hippocampus of the rat brain during chronic unpredictable stress

A Ahmad, N Rasheed, N Banu, G Palit - Stress, 2010 - Taylor & Francis
Stress plays a key role in the induction of various clinical disorders by altering
monoaminergic response and antioxidant defenses. In the present study, alterations in the …

Effect of Bacopa monniera on stress induced changes in plasma corticosterone and brain monoamines in rats

N Sheikh, A Ahmad, KB Siripurapu… - Journal of …, 2007 - Elsevier
Bacopa monniera (BM) is well known for its neuropharmacological effects. Our previous
studies indicated the adaptogenic effect of standardized extract of BM in various stress …

Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain in Sprague-Dawley rats: Emphasis on the modulation of oxidative stress and …

MA Ali, ET Menze, MG Tadros, MF Tolba - Neuropharmacology, 2020 - Elsevier
Chemotherapy-induced cognitive dysfunction (chemobrain) is one of the major complaints
for cancer patients treated with chemotherapy such as Doxorubicin (DOX). The induction of …

[HTML][HTML] Vildagliptin restores cognitive function and mitigates hippocampal neuronal apoptosis in cisplatin-induced chemo-brain: imperative roles of AMPK/Akt/CREB …

AMA Mahmoud, EM Mantawy, SA Wahdan… - Biomedicine & …, 2023 - Elsevier
Cisplatin (CP) is a broad-spectrum antineoplastic agent used to treat many human cancers.
Nonetheless, most patients receiving CP suffer from cognitive deficits, a phenomenon …

Noise and brain

A Arjunan, R Rajan - Physiology & Behavior, 2020 - Elsevier
Noise has become inexorable stress due to the increase in urbanization, automobile usage,
Noise based occupation, and lifestyle modifications such as recreation in day to day life of …

Effect of maternal separation and chronic stress on hippocampal-dependent memory in young adult rats: Evidence for the match-mismatch hypothesis

MI Zalosnik, A Pollano, V Trujillo, MM Suarez… - Stress, 2014 - Taylor & Francis
Adverse experiences early in life may sensitize the hippocampus to subsequent stressors
throughout the individual's life. We analyzed in male rats, whether, the interaction between …