Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics

H Chen, C Chen, M Spanos, G Li, R Lu, Y Bei… - … and Targeted Therapy, 2022 - nature.com
Exercise training has been widely recognized as a healthy lifestyle as well as an effective
non-drug therapeutic strategy for cardiovascular diseases (CVD). Functional and …

Exercise‐induced oxidative stress: past, present and future

SK Powers, Z Radak, LL Ji - The Journal of physiology, 2016 - Wiley Online Library
The existence of free radicals in living cells was first reported in 1954 and this important
finding helped launch the field of free radical biology. However, the discovery that muscular …

Heat shock proteins in oxidative stress and ischemia/reperfusion injury and benefits from physical exercises: a review to the current knowledge

J Szyller, I Bil-Lula - Oxidative Medicine and Cellular Longevity, 2021 - Wiley Online Library
Heat shock proteins (HSPs) are molecular chaperones produced in response to oxidative
stress (OS). These proteins are involved in the folding of newly synthesized proteins and …

Exercise and cardiac health: physiological and molecular insights

JBN Moreira, M Wohlwend, U Wisløff - Nature Metabolism, 2020 - nature.com
The cardiac benefits of exercise have been recognized for centuries. Studies have
undisputedly shown that regular exercise is beneficial for the cardiovascular system in …

Manganese superoxide dismutase and oxidative stress modulation

G Bresciani, IBM da Cruz… - Advances in clinical …, 2015 - Elsevier
Oxidative stress is characterized by imbalanced reactive oxygen species (ROS) production
and antioxidant defenses. Two main antioxidant systems exist. The nonenzymatic system …

Hypoxia-induced oxidative stress modulation with physical activity

T Debevec, GP Millet, V Pialoux - Frontiers in physiology, 2017 - frontiersin.org
Increased oxidative stress, defined as an imbalance between prooxidants and antioxidants,
resulting in molecular damage and disruption of redox signaling, is associated with …

Mechanisms of exercise-induced cardioprotection

SK Powers, AJ Smuder, AN Kavazis… - Physiology, 2014 - journals.physiology.org
Myocardial ischemia-reperfusion (IR) injury can cause ventricular cell death and is a major
pathological event leading to morbidity and mortality in those with coronary artery disease …

Prolonged mechanical ventilation alters diaphragmatic structure and function

SK Powers, AN Kavazis, S Levine - Critical care medicine, 2009 - journals.lww.com
Objective: To review current knowledge about the impact of prolonged mechanical
ventilation on diaphragmatic function and biology. Measurements: Systematic literature …

Modulation of anthracycline-induced cardiotoxicity by aerobic exercise in breast cancer: current evidence and underlying mechanisms

JM Scott, A Khakoo, JR Mackey, MJ Haykowsky… - Circulation, 2011 - Am Heart Assoc
Anthracycline-containing chemotherapy (eg, doxorubi-cin) is well known to cause dose-
dependent, progressive cardiac damage clinically manifest as decreased left ventricular …

Conserving wildlife in a changing world: Understanding capture myopathy—A malignant outcome of stress during capture and translocation

D Breed, LCR Meyer, JCA Steyl… - Conservation …, 2019 - academic.oup.com
The number of species that merit conservation interventions is increasing daily with ongoing
habitat destruction, increased fragmentation and loss of population connectivity …