Radiation damage inflicted during diffraction data collection in macromolecular
crystallography has re-emerged in the last decade as a major experimental and …

Radiation damage is an unwelcome and unavoidable aspect of macromolecular
crystallography. In order to quantify the extent of X-ray-induced changes, knowledge of the …

In macromolecular crystallography, the acquisition of a complete set of diffraction intensities
typically involves a high cumulative dose of X-ray radiation. In the process of data …

ID14-4 at the ESRF is the first tunable undulator-based macromolecular crystallography
beamline that can celebrate a decade of user service. During this time ID14-4 has not only …

In an X-ray diffraction experiment, the structure of molecules and the crystal lattice changes
owing to chemical reactions and physical processes induced by the absorption of X-ray …

Anomalous difference Fourier maps derived from the diffraction data collected at both
standard and long-wavelength X-rays were compared. The discrepancies observed in the …

A method of analysis is presented that allows for the separation of specific radiation-induced
changes into distinct components in real space. The method relies on independent …

The most commonly used heavy-atom derivative, selenium, requires the use of a tunable
beamline to access the Se K edge for experimental phasing using anomalous diffraction …

Diffraction intensities measurements are influenced by random errors and complex patterns
of systematic effects. The systematic effects can be physically modeled if their sources are …