[HTML][HTML] Packaging signal of influenza A virus
X Li, M Gu, Q Zheng, R Gao, X Liu - Virology Journal, 2021 - Springer
Influenza A virus (IAV) contains a genome with eight single-stranded, negative-sense RNA
segments that encode 17 proteins. During its assembly, all eight separate viral RNA (vRNA) …
segments that encode 17 proteins. During its assembly, all eight separate viral RNA (vRNA) …
[HTML][HTML] Hemagglutinin subtype specificity and mechanisms of highly pathogenic avian influenza virus genesis
ACM de Bruin, M Funk, MI Spronken, AP Gultyaev… - Viruses, 2022 - mdpi.com
Highly Pathogenic Avian Influenza Viruses (HPAIVs) arise from low pathogenic precursors
following spillover from wild waterfowl into poultry populations. The main virulence …
following spillover from wild waterfowl into poultry populations. The main virulence …
[HTML][HTML] A structure-based model for the complete transcription cycle of influenza polymerase
JM Wandzik, T Kouba, M Karuppasamy, A Pflug… - Cell, 2020 - cell.com
Influenza polymerase uses unique mechanisms to synthesize capped and polyadenylated
mRNAs from the genomic viral RNA (vRNA) template, which is packaged inside …
mRNAs from the genomic viral RNA (vRNA) template, which is packaged inside …
The influenza A virus genome packaging network—complex, flexible and yet unsolved
C Jakob, R Paul-Stansilaus, M Schwemmle… - Nucleic Acids …, 2022 - academic.oup.com
The genome of influenza A virus (IAV) consists of eight unique viral RNA segments. This
genome organization allows genetic reassortment between co-infecting IAV strains …
genome organization allows genetic reassortment between co-infecting IAV strains …
[HTML][HTML] Mapping of influenza virus RNA-RNA interactions reveals a flexible network
V Le Sage, JP Kanarek, DJ Snyder, VS Cooper… - Cell reports, 2020 - cell.com
Selective assembly of influenza virus segments into virions is proposed to be mediated
through intersegmental RNA-RNA interactions. Here, we developed a method called …
through intersegmental RNA-RNA interactions. Here, we developed a method called …
In vivo analysis of influenza A mRNA secondary structures identifies critical regulatory motifs
LM Simon, E Morandi, A Luganini… - Nucleic acids …, 2019 - academic.oup.com
The influenza A virus (IAV) is a continuous health threat to humans as well as animals due to
its recurring epidemics and pandemics. The IAV genome is segmented and the eight …
its recurring epidemics and pandemics. The IAV genome is segmented and the eight …
Selective genome packaging mechanisms of influenza A viruses
T Noda - Cold Spring Harbor Perspectives in …, 2021 - perspectivesinmedicine.cshlp.org
The genome of influenza A virus (IAV) comprises eight segmented, single-stranded,
negative-sense RNAs. The genome packaging mechanism of IAV was a long-standing …
negative-sense RNAs. The genome packaging mechanism of IAV was a long-standing …
[HTML][HTML] Parallel evolution between genomic segments of seasonal human influenza viruses reveals RNA-RNA relationships
JE Jones, V Le Sage, GH Padovani, M Calderon… - Elife, 2021 - elifesciences.org
The influenza A virus (IAV) genome consists of eight negative-sense viral RNA (vRNA)
segments that are selectively assembled into progeny virus particles through RNA-RNA …
segments that are selectively assembled into progeny virus particles through RNA-RNA …
[HTML][HTML] Next-generation sequencing: A new avenue to understand viral RNA–protein interactions
The genomes of RNA viruses present an astonishing source of both sequence and structural
diversity. From intracellular viral RNA-host interfaces to interactions between the RNA …
diversity. From intracellular viral RNA-host interfaces to interactions between the RNA …
RNA sequence features are at the core of influenza a virus genome packaging
M Shafiuddin, ACM Boon - Journal of molecular biology, 2019 - Elsevier
The influenza A virus (IAV), a respiratory pathogen for humans, poses serious medical and
economic challenges to global healthcare systems. The IAV genome, consisting of eight …
economic challenges to global healthcare systems. The IAV genome, consisting of eight …