[HTML][HTML] Lin28 regulates cancer cell stemness for tumour progression
Simple Summary Cancer stem cells (CSCs) are a small population of tumour cells bearing
stemness characteristics. They have been deemed as a root of cancer development and a …
stemness characteristics. They have been deemed as a root of cancer development and a …
Phenotypic plasticity-alternate transcriptional programs driving treatment resistant prostate cancer
Androgen deprivation therapy (ADT) that antagonizes androgen receptor (AR) signaling has
made significant increases to overall survival of prostate cancer patients. However, ADT is …
made significant increases to overall survival of prostate cancer patients. However, ADT is …
miR-140-5p protects cartilage progenitor/stem cells from fate changes in knee osteoarthritis
Y Chen, H Huang, W Zhong, L Li, Y Lu, H Si - International …, 2023 - Elsevier
Cartilage progenitor/stem cells (CPCs) are promising seed cells for cartilage regeneration,
but their fate changes and regulatory mechanisms in osteoarthritis (OA) pathogenesis …
but their fate changes and regulatory mechanisms in osteoarthritis (OA) pathogenesis …
Injectable hydrogel harnessing foreskin mesenchymal stem cell-derived extracellular vesicles for treatment of chronic diabetic skin wounds
C Xu, JF Cao, Y Pei, Y Kim, H Moon, CQ Fan… - Journal of Controlled …, 2024 - Elsevier
Chronic skin wounds are a serious complication of diabetes with a high incidence rate,
which can lead to disability or even death. Previous studies have shown that mesenchymal …
which can lead to disability or even death. Previous studies have shown that mesenchymal …
YY1/miR-140-5p/Jagged1/Notch axis mediates cartilage progenitor/stem cells fate reprogramming in knee osteoarthritis
Y Chen, G Liao, T Ma, L Li, J Yang, B Shen… - International …, 2023 - Elsevier
Osteoarthritis is a multifactorial disease characterized by cartilage degeneration, while
cartilage progenitor/stem cells (CPCs) are responsible for endogenous cartilage repair …
cartilage progenitor/stem cells (CPCs) are responsible for endogenous cartilage repair …
Design, synthesis and activity evaluation of quinolinone derivatives as EZH2 inhibitors
J Cai, H You, X Qin, Y Wang, W Li - Bioorganic & Medicinal Chemistry …, 2024 - Elsevier
The enhancer of zeste homologue 2 (EZH2) is the core catalytic subunit of polycomb
repressive complex 2, which catalyzes lysine 27 methylation of histone H3. Herein, a series …
repressive complex 2, which catalyzes lysine 27 methylation of histone H3. Herein, a series …
Reconstructing the lung stem cell niche in vitro
Lungs are constantly exposed to a variety of environmental hazards and undergo injury. In
response to injury, a reservoir of lung stem cells undergoes rapid self-renewal, proliferation …
response to injury, a reservoir of lung stem cells undergoes rapid self-renewal, proliferation …