A virtual patient simulation modeling the neural and perceptual effects of human visual cortical stimulation, from pulse trains to percepts
I Fine, GM Boynton - Scientific Reports, 2024 - nature.com
The field of cortical sight restoration prostheses is making rapid progress with three clinical
trials of visual cortical prostheses underway. However, as yet, we have only limited insight …
trials of visual cortical prostheses underway. However, as yet, we have only limited insight …
An in-silico framework for modeling optimal control of neural systems
B Rueckauer, M van Gerven - Frontiers in Neuroscience, 2023 - frontiersin.org
Introduction Brain-machine interfaces have reached an unprecedented capacity to measure
and drive activity in the brain, allowing restoration of impaired sensory, cognitive or motor …
and drive activity in the brain, allowing restoration of impaired sensory, cognitive or motor …
Theoretical analysis of optogenetic spiking with ChRmine, bReaChES and CsChrimson-expressing neurons for retinal prostheses
Objective. Optogenetics has emerged as a promising technique for neural prosthetics,
especially retinal prostheses, with unprecedented spatiotemporal resolution. Newly …
especially retinal prostheses, with unprecedented spatiotemporal resolution. Newly …
Theoretical prediction of broadband ambient light optogenetic vision restoration with ChRmine and its mutants
Vision restoration is one of the most promising applications of optogenetics. However, it is
limited due to the poor-sensitivity, slow-kinetics and narrow band absorption spectra of …
limited due to the poor-sensitivity, slow-kinetics and narrow band absorption spectra of …
[PDF][PDF] Bridging model and experiment in systems neuroscience with Cleo: the Closed-Loop, Electrophysiology, and Optophysiology simulation testbed
KA Johnsen, NA Cruzado, ZC Menard, AA Willats… - bioRxiv, 2023 - scholar.archive.org
Recent advances in neurotechnology enable exciting new experiments, including novel
paradigms such as closed-loop optogenetic control that achieve powerful causal …
paradigms such as closed-loop optogenetic control that achieve powerful causal …
Optogenetic activation of visual thalamus generates artificial visual percepts
J Wang, H Azimi, Y Zhao, M Kaeser, PV Sánchez… - Elife, 2023 - elifesciences.org
The lateral geniculate nucleus (LGN), a retinotopic relay center where visual inputs from the
retina are processed and relayed to the visual cortex, has been proposed as a potential …
retina are processed and relayed to the visual cortex, has been proposed as a potential …
Bridging model and experiment in systems neuroscience with Cleo: the Closed-Loop, Electrophysiology, and Optophysiology simulation testbed
KA Johnsen, NA Cruzado, ZC Menard, AA Willats… - …, 2024 - pmc.ncbi.nlm.nih.gov
Systems neuroscience has experienced an explosion of new tools for reading and writing
neural activity, enabling exciting new experiments such as all-optical or closed-loop control …
neural activity, enabling exciting new experiments such as all-optical or closed-loop control …
Optogenetic stimulation recruits cortical neurons in a morphology-dependent manner
Single-photon optogenetic stimulation is a crucial tool in neuroscience, enabling precise,
cell-type-specific modulation of neuronal circuits. Miniaturization of this technique in the form …
cell-type-specific modulation of neuronal circuits. Miniaturization of this technique in the form …
Iso-orientation bias of layer 2/3 connections: the unifying mechanism of spontaneous, visually and optogenetically driven V1 dynamics
T Rózsa, R Cagnol, J Antolík - bioRxiv, 2024 - biorxiv.org
Functionally specific long-range lateral connectivity in layer 2/3 of the primary visual cortex
(V1) supports the integration of visual information across visual space and shapes …
(V1) supports the integration of visual information across visual space and shapes …
Optimal Control of Neural Systems
B Rueckauer, M van Gerven - bioRxiv, 2022 - biorxiv.org
Brain-machine interfaces have reached an unprecedented capacity to measure and drive
activity in the brain, allowing restoration of impaired sensory, cognitive or motor function …
activity in the brain, allowing restoration of impaired sensory, cognitive or motor function …