Multiple sclerosis (MS) is a chronic, progressive disorder of the central nervous system
(CNS) that affects more than two million people worldwide. Several animal models resemble …

Multiple sclerosis (MS) is widely considered to be the result of an aggressive autoreactive T
cell attack on myelin. How these autoimmune responses arise in MS is unclear, but they …

Multiple sclerosis (MS) is a neurological disease characterized by multifocal lesions and
smoldering pathology. Although single-cell analyses provided insights into cytopathology …

Patients suffering from neuropathic pain have a higher incidence of mood disorders such as
depression. Increased expression of tumor necrosis factor (TNF) has been reported in …

Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system
(CNS). Interferon (IFN)-β constitutes one of the first-line therapies to treat MS, but has limited …

Although the primary cause of multiple sclerosis (MS) is unknown, the widely accepted view
is that aberrant (auto) immune responses possibly arising following infection (s) are …

The identification of a drug that stimulates endogenous myelination and spares axon
degeneration during multiple sclerosis (MS) could potentially reduce the rate of disease …

Animal models of multiple sclerosis (MS), specifically experimental autoimmune
encephalomyelitis (EAE), have been used extensively to develop anti-inflammatory …

Multiple sclerosis (MS) is a disabling neurodegenerative disease that causes demyelination
and axonal degeneration of the central nervous system. Current treatments are partially …

Currently available immunomodulatory therapies do not stop the pathogenesis underlying
multiple sclerosis (MS) and are only partially effective in preventing the onset of permanent …