A new paradigm for generating high-quality cardiac pacemaker cells from mouse pluripotent stem cells
Z Lin, B Lin, C Hang, R Lu, H Xiong, J Liu… - … and Targeted Therapy, 2024 - nature.com
Cardiac biological pacing (BP) is one of the future directions for bradyarrhythmias
intervention. Currently, cardiac pacemaker cells (PCs) used for cardiac BP are mainly …
intervention. Currently, cardiac pacemaker cells (PCs) used for cardiac BP are mainly …
[HTML][HTML] Differentiation of Sinoatrial-like Cardiomyocytes as a Biological Pacemaker Model
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are widely used
for disease modeling and pharmacological screening. However, their application has mainly …
for disease modeling and pharmacological screening. However, their application has mainly …
Single-cell transcriptome analysis reveals CD34 as a marker of human sinoatrial node pacemaker cardiomyocytes
The sinoatrial node regulates the heart rate throughout life. Failure of this primary
pacemaker results in life-threatening, slow heart rhythm. Despite its critical function, the …
pacemaker results in life-threatening, slow heart rhythm. Despite its critical function, the …
Fluorescent hiPSC-derived MYH6-mScarlet cardiomyocytes for real-time tracking, imaging, and cardiotoxicity assays
R Maria Cherian, C Prajapati, K Penttinen… - Cell Biology and …, 2023 - Springer
Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) hold great
potential in the cardiovascular field for human disease modeling, drug development, and …
potential in the cardiovascular field for human disease modeling, drug development, and …
[图书][B] Modeling the Impact of the Autonomic Nervous System on the Development of Human iPSC-Sinoatrial Nodal Cells
J King - 2023 - search.proquest.com
The sinoatrial (SA) node initiates the heart's electrical impulse as the primary pacemaker.
Since it leads the cardiac conduction system, its maturation at the tissue and cellular level …
Since it leads the cardiac conduction system, its maturation at the tissue and cellular level …
CRISPR/Cas9-mediated engineering of subtype-specific cell lines for iPSC-derived cardiomyocyte phenotyping
N Sontayananon - 2022 - ora.ox.ac.uk
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) represent a useful tool for
cardiovascular research. However, the mixed subtypes, including atrial-like, ventricular-like …
cardiovascular research. However, the mixed subtypes, including atrial-like, ventricular-like …