Promoter G-quadruplex binding styryl benzothiazolium derivative for applications in ligand affinity ranking and as ethidium bromide substitute in gel staining

RK Patidar, K Tiwari, R Tiwari… - ACS Applied Bio …, 2023 - ACS Publications
Fluorescent compounds that can preferentially interact with certain nucleic acids are of great
importance in new drug discovery in a multitude of functions including fluorescence-based …

Coronavirus genomic cDNA derived G-quadruplex as a selective target for fluorometric detection

S Pratihar, MN Mattath, T Govindaraju - Chemical Communications, 2023 - pubs.rsc.org
Pathogenic genomes harboring noncanonical G-quadruplex (GQ) forming sequences are
potential targets for diagnosis. The GQ-forming cDNA sequences of SARS-CoV-2 (Severe …

Human telomeric G-quadruplex DNA enabled preferential recognition of copper (II) and Iron (III) ions sensed by a red emissive probe

P Ombase, RK Patidar, L Singh, J Baranwal… - Tetrahedron …, 2022 - Elsevier
Metal ions regulate several cellular processes in humans and other life forms and their
balance in the body is essential for a healthy life. Specific detection of metal ions is important …

Preferential Binding of a Red Emissive Julolidine Derivative to a Promoter G‐Quadruplex

S Metangle, N Ranjan - ChemBioChem, 2024 - Wiley Online Library
The therapeutic potential of G‐quadruplexes has increased significantly with the growing
understanding of their functional roles in pathogens apart from human diseases such as …